Traditional Chinese Medicine Constitutional Distribution And Associated Risk Facyors In Helicobacter Pylori Infection

Objective:The purpose of this study is to investigate the distribution of TCM constitution of patients with Helicobacter pylori infection,and explore the influence of TCM constitution,physical characteristics,lipid levels,living and eating and exercise habits and other factors on Helicobacter pylori infection,analyze the possible risk factors of Helicobacter pylori infection,and provide scientific basis for the prevention and intervention of Helicobacter pylori infection.Methods:This subject is a cross-sectional study.By selecting 450 physical examination personnel from the physical examination center of the First Affiliated Hospital of Heilongjiang University of traditional Chinese medicine(all tested for Helicobacter pylori infection),Among them,161 cases in the Hp infection group and 289 cases in non Hp infection group named Hp control group,which met the inclusion criteria.The medical stuff from the physical examination center will distribute the questionnaire to the physical examination personnel on the spot,guide the respondents to fill in the questionnaire and recover the questionnaire on the spot.The contents of the questionnaires include the TCM constitution classification scale and the health risk factor assessment,spss20.0 statistics software was applied to the results to analyze the data.Results:1.In terms of physical characteristics,there were significant differences in body weight,waist circumference and BMI between Hp infection group and Hp control group(P<0.05).2.In terms of TCM Constitution distribution,the frequencies of TCM Constitution types in Hp infection group from high to low were peaceful quality in 43 cases(26.71%),damp-heat in 31 cases(19.25%),yang deficiency in 28 cases(17.40%),phlegm-dampness in 18 cases(11.18%),qi-deficiency in 11 cases(6.83%),yin-deficiency in 11 cases(6.83%),blood stasis in 11 cases(6.83%),qi-stagnation in5 cases(3.11%)and intrinsic quality in 3 cases(1.86%);In the Hp control group,the frequencies of TCM constitution types from high to low were 97 cases of peaceful quality(33.56%),69 cases of yang deficiency(23.88%),29 cases of damp-heat(10.03%),27 cases of phlegm-dampness(9.34%),24 cases of qi-deficiency(8.30%),15 cases of qi-stagnation(5.19%),11 cases of yin-deficiency(3.81%),9 cases of blood stasis(3.11%)and 8 cases of intrinsic quality(2.77%).The difference of damp-heat quality between the two groups was statistically significant(P<0.05).3.In the age group,there was significant difference in damp-heat between Hp infection group and HP control group in youth group(P<0.05),and there was significant difference in yang deficiency and blood stasis between the two groups in elderly group(P<0.05).In the waist circumference group,there was significant difference in peaceful quality,qi-deficiency and damp-heat between the two groups(P<0.05).In BMI group,there was significant difference between the two groups in peaceful quality and damp-heat quality in obesity group(P<0.05).4.In living and eating habits,passive smoking,intake of bean products and dietary preference for oil were correlated with Hp infection(P<0.05).5.In binary regression analysis,HP infection was positively correlated with body weight,diet preference for oil,damp heat constitution,and negatively correlated with edible bean products;In the HP infection group,those with mild physique were positively correlated with exercise intensity and diet preference,and negatively correlated with sleep disorder;There was a positive correlation between damp heat constitution and BMI classification(lean,normal,overweight,obesity)in HP infection group;There was a positive correlation between HP deficiency and HP infection.Conclusion:1.The distribution of TCM Constitution in patients with HP infection is more common in peaceful quality,damp-heat and yang-deficiency.Among them,damp-heat may be the susceptible constitution of HP infection.Damp-heat may be the susceptible constitution of young people to HP infection,and yang-deficiency may be the susceptible constitution of middle-aged and elderly people to HP infection.2.There were differences in TCM Constitution distribution between the Hp infection group and Hp control group under the same physical characteristics.3.In this study,Hp infection has nothing to do with drinking,sleeping,exercise,psychological pressure and lipid levels.Weight,oily diet and damp-heat may be the risk factors of HP infection,and the intake of bean products may be the protective factors of HP infection.