Objective:To discuss the effect of modified encephalo-duro-arterio-synangiosis surgery(EDAS)on cognitive and nerve function in patients with internal carotid artery or middle cerebral artery occlusion.Methods:Fifty-four patients with internal carotid artery or middle cerebral artery occlusion were selected and divided into modified EDAS group and control group according to different treatment methods.The changes in cerebral hemodynamic,cognitive and nerve functions in the two groups were observed at 1 years after surgery.Results:Control group patients with baseline and 1 year after discharge,CBF,determined by MTT,TTP comparison,there were no statistically significant difference(P= 0.065,0.938,0.134),those who did EDAS in baseline and 1 year after discharge,CBF,determined by MTT,TTP comparison,the difference had statistical significance(P < 0.05).Control group patients with baseline and 1 year after discharge MOCA and MMSE scale for comparison,the difference had no statistical significance(P = 0.232,0.355),those who did EDAS in baseline and 1 year after discharge MOCA and MMSE scale comparison,the difference had statistical significance(P < 0.05).Baseline control group patients compared with m RS scale 1 year after discharge,there were no statistically significant difference(P= 0.351),EDAS baseline surgical patients compared with m RS scale 1 year after discharge,the difference had statistical significance.Two groups of patients at baseline CBF,determined by MTT,TTP,MOCA and MMSE scale,m RS rating scale difference had no statistical significance,followed up for 1 years later,the surgical patients increased CBF,determined by MTT and TTP is reduced,MOCA and MMSE score are promoted,m RS lower scores.Conclusion: the prognosis of patients with EDAS scores,EDAS surgery can improve chronic internal carotid artery occlusion or middle cerebral artery occlusion in patients with cerebral blood flow dynamics and cognitive and neural function. |