| Purpose: In this study,clinical randomized controlled trials were conducted to observe the improvement of clinical symptom scores and immune inflammatory indexes of Allergic Rhinitis(AR)with lung Qi deficiency and cold type treated by mild moxibustion,and to evaluate the clinical efficacy of mild moxibustion in the treatment of lung Qi deficiency and cold type AR.The value of the anti-inflammatory and immune effects of moxibustion in the treatment of immune inflammatory diseases was analyzed and discussed.Thus,it provides effective treatment plan and objective basis for mild moxibustion treatment of lung Qi deficiency cold type AR.Methods: After clinical ethical review,70 patients with lung Qi deficiency and cold type AR in the Department of Otolaryngology,Affiliated Hospital of Gansu University of Traditional Chinese Medicine from November 1,2021 to December 1,2022 were selected and randomly divided into control group(35 cases)and treatment group(35 cases).The control group was given loratadine tablets,orally,10mg/ time,once a day,once a time,1tablet,1 week as a course of treatment,a total of 4 courses of treatment.The treatment group was treated with mild moxibustion therapy.Select the main points: Yingxiang point,Yintang point.Matching points: Dazhui point,bilateral Feishu point and bilateral Zusanli point,moxibustion once every other day,moxibustion 3 times a week.One week is one course of treatment.The Total score of nasal symptoms(TNSS),TCM syndrome scores,and laboratory indicators were recorded 1 month after the treatment,one day before and one day after the end of the treatment.The levels of Immunoglobulin E(IgE)and Eosinophils(EOS),and the overall efficacy was evaluated after the end of treatment,and the data were analyzed by SPSS26.0 software.Results:1.Baseline data analysis: Age,gender,course of disease and observation indicators before treatment were statistically analyzed in the two groups(P > 0.05),indicating that subjects in the two groups were evenly distributed and comparable.2.Comparison of TNSS scores: Intra-group comparison: TNSS scores of the treatment group and control group after treatment were compared with those before treatment,and the differences were statistically significant(P < 0.05).TNSS scores of treatment group and control group 1 month after treatment were significantly different from those before treatment(P < 0.05).Comparison between groups: After treatment,TNSS scores of control group and treatment group were significantly different(P < 0.05).The TNSS scores of the two groups were significantly different 1 month after treatment(P < 0.05).3.Comparison of single symptom scores in TNSS: Intra-group comparison: The single symptom scores in TNSS after treatment were statistically significant between the treatment group and the control group compared with those before treatment(P < 0.05).Comparison between groups: There were statistically significant differences in nasal congestion and runny nose scores between the treatment group and the control group after treatment(P < 0.05),but no statistically significant differences in nasal itching and sneezing scores between the treatment group and the control group(P > 0.05).4.Comparison of TCM syndrome scores: intra-group comparison: TCM syndrome scores of treatment group and control group after treatment were compared with those before treatment,the difference was statistically significant(P < 0.05);Comparison between groups:There was statistical significance in TCM syndrome scores between the treatment group and the control group after treatment(P < 0.05).5.Comparison of serum total IgE level: Intra-group comparison: The serum total IgE level of the treatment group and the control group after treatment was compared with that before treatment,and the difference was statistically significant(P < 0.05).Comparison between groups: There was statistical significance in serum total IgE level between the treatment group and the control group after treatment(P < 0.05).6.Comparison of EOS level: Intra-group comparison: The EOS level of the treatment group and the control group after treatment was significantly different from that before treatment(P < 0.01);Comparison between groups: There was statistical significance in EOS level between treatment group and control group after treatment(P < 0.05).7.Overall curative effect analysis: in the control group,6 cases were effective,19 cases were effective,8 cases were ineffective;In the treatment group,11 cases were effective,20 cases were effective and 2 cases were ineffective.The overall curative effect of the treatment group was better than that of the control group,and the difference was statistically significant(P < 0.05).Conclusion:1.Both mild moxibustion and conventional western medicine are effective for lung Qi deficiency cold type AR,but mild moxibustion has better curative effect.2.Mild moxibustion is more obvious in reducing the total score of nasal symptoms of lung-qi deficiency cold type AR,among which mild moxibustion is more obvious in improving nasal congestion and runny nose of this disease,and mild moxibustion is better than conventional western medicine in improving nasal symptoms in the long term.3.Mild moxibustion is superior to conventional western medicine in improving the TCM syndrome of lung Qi deficiency cold type AR.4.Mild moxibustion is superior to conventional western medicine in improving IgE level and EOS level of lung Qi deficiency cold type AR. |
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