Analysis Of The Factors Influencing The Positive Rate Of Transrectal Ultrasound-guided Needle Biopsy For Prostate Cancer

Objective(s):A retrospective analysis was conducted on 353 cases of prostate disease patients collected in our hospital in the past year,and the factors affecting the positive rate of prostate puncture were systematically analyzed.At the same time,whether there was a significant correlation between different examination postures and the positive detection rate of prostate cancer was explored,hoping to find the main factors affecting male prostate cancer in our area and find the optimal examination postures.To increase the positive detection rate of prostate cancer.Method:The main information of patients receiving TRUS prostate biopsy in The Second Affiliated Hospital of Kunming Medical University from May 2021 to September2022 was collected,including clinically important age,prostate size,pre-puncture PSA related values and some postoperative pathological results.A total of 353 patients were collected under two different examination methods.The 353 patients were composed of 211 patients examined in half chest and knee position and 142 patients examined in left decubitus position.First,an overall analysis of the factors affecting the positive rate of PCa in 353 patients was conducted to obtain a general rule.Then,the differences of laboratory test indicators,positive rate,pathological results and other information before puncture were statistically analyzed and compared between the two groups,to explore whether there was a correlation between the two different lying modes and the positive rate of puncture.It is expected that relevant conclusions will be helpful to improve the diagnosis rate of early PCa.Results:353 Patients with prostate puncture were divided into two groups according to puncture posture: half thoracic knee position and left lateral position.Statistical analysis was conducted on all patients and patients in each group.Among 353 patients,136 were diagnosed with prostate cancer,with a positive rate of 38.527%,and 119 were artificial hyperplasia,accounting for 33.711%.81 artificial hyperplasia with mild inflammation,accounting for 22.946%;7 were artificial hyperplasia with moderate inflammation,accounting for 1.983%;5 patients were nonspecific granulomatous prostatitis,accounting for 1.416%.Univariate analysis showed that age,t PSA and PSAD were positively correlated with the positive rate of prostate puncture,PV and f/t PSA were negatively correlated with the positive rate of prostate puncture,but BMI was not correlated with the positive rate of prostate puncture.At the same time,although statistical analysis found that the PCa positive rate in the left decubitus group was 7.413 percentage points higher than that in the half chest knee group,there was no statistically significant difference between the half chest knee position and the left decubitus position.In addition,by refining the age and t PSA interval and conducting comparative analysis between the two groups,it was found that there was no significant difference in puncture positive rate between the two groups at different ages and t PSA levels.Multiple logistic regression analysis of statistically significant influencing factors showed that age and PSAD were the most important independent influencing factors on the positive rate of prostate cancer.Conclusion(s):The main factors affecting the risk of prostate cancer are age and PSAD.There was no statistically significant difference in the detection rate of prostate cancer between the half chest and knee position and the left decubitus position,but the positive rate of PCa in the left decubitus position was 7.413 percentage points higher than that in the half chest and knee position.In a sense,the left decubitus position was helpful to improve the positive rate of prostate cancer.