Clinical Observation On The Efficacy Of Combined Internal And External Treatment In The Treatment Of Perimenopausal Insomni

Purpose:By observing the clinical efficacy of oral traditional Chinese medicine combined with external acupoint application therapy and oral traditional Chinese medicine alone on perimenopausal insomnia patients with liver and kidney yin deficiency,and comparing the improvement of the two treatment methods on sleep quality,perimenopausal vasomotor and systolic symptoms,autonomic nerve disorder symptoms,psychoneurological symptoms,etc,To analyze and explore the causes of the difference between internal and external treatment combined with simple oral administration of traditional Chinese medicine in the treatment of perimenopausal insomnia with liver and kidney yin deficiency,so as to provide reference basis for the clinical application of the treatment of perimenopausal insomnia with liver and kidney yin deficiency.Material and method:The subjects of this study were all outpatients in the Affiliated Hospital of Liaoning University of traditional Chinese medicine.56 subjects who were diagnosed by traditional Chinese medicine as consistent with pre menopausal and post menopausal syndromes and insomnia,and those diagnosed by western medicine as consistent with menopausal syndrome and non organic insomnia were included in this study.Using the method of randomized controlled trial,56 qualified subjects were randomly divided into observation group and control group,with 28 cases in each group.The control group was treated with Zishen tiaogan decoction,a tutor’s experience.One week was a course of treatment,and four courses of treatment were treated continuously.On the basis of the treatment method of the control group,the observation group was treated with external treatment(Yongquan acupoint application).Acupoint application for 5 days was a course of treatment,with an interval of 2 days between each course of treatment,a total of 4 courses of treatment.The Pittsburgh sleep index scale(PSQI)was used to evaluate the sleep quality,the female menopause self-test scale(improved Kupperman score)was used to evaluate the severity of perimenopausal symptoms,the TCM syndrome integral scale was used to evaluate the corresponding TCM syndromes,and the insomnia efficacy evaluation standard was used to evaluate the efficacy.The subjects’ sleep time,sleep efficiency and daytime dysfunction were observed to evaluate the sleep quality.To observe the changes of perimenopausal symptoms such as hot flashes,sweating,emotional disorders,palpitation and headache,as well as liver and kidney yin deficiency symptoms such as waist and knee soreness and five heart upset and heat,and to record all adverse events and adverse reactions of patients during the treatment,so as to explore the curative effect and difference between the two groups in the treatment of perimenopausal insomnia patients.All clinical study data were collected by spss26 The statistical software version 0 was used for data statistical analysis,and the test result was p < 0.05,which represented that the difference between the data was statistically significant.Results:1.Baseline data analysis: there was no significant difference in age and course of disease between the two groups(P > 0.05).There was no significant difference in PSQI score,modified Kupperman score and TCM syndrome score between the two groups before treatment(P > 0.05).2.Before and after treatment,the total score of PSQI,sub scores,improved Kupperman score and TCM syndrome score of the observation group and the control group decreased,and the difference was statistically significant(P < 0.05).3.After treatment,there were significant differences in sleep quality,sleep time,sleep time and sleep disorder between the observation group and the control group(P < 0.05),but there was no significant difference in sleep efficiency and daytime dysfunction(P > 0.05).After treatment,there was significant difference in the improved Kupperman score and TCM syndrome score between the observation group and the control group(P < 0.05).4.During the test,1 case in the observation group fell off,1 case in the control group fell off,1 case in the observation group fell off because the skin broke and could not be treated continuously according to the course of treatment after failing to comply with the doctor’s advice for a long time,and 1 case in the control group fell off because he could not adhere to the treatment for personal reasons.There were no serious adverse reactions in both groups during the treatment.Conclusion:1.Oral administration of Zishen tiaogan decoction can improve the sleep quality and perimenopausal symptoms of perimenopausal insomnia patients with liver and kidney yin deficiency.2.Oral administration of Zishen tiaogan decoction is effective in prolonging sleep time and improving daytime dysfunction,but it does not significantly improve the symptoms of difficulty falling asleep.3.Acupoint application therapy can significantly shorten the time for patients to fall asleep and improve sleep disorders.4.Zishen tiaogan decoction combined with acupoint application can better improve the sleep quality of perimenopausal insomnia patients with liver and kidney yin deficiency,shorten the sleep time,prolong the sleep time,alleviate sleep disorders and improve perimenopausal symptoms.