Clinical Observation Of Ziyin Qingre Decoction In Treating Insomnia Of Yin Deficiency Of Liver And Kidney

Objective:To evaluate the safety and effectiveness of Nourishing Yin and clearing heat prescription in the treatment of insomnia with deficiency of liver and kidney yin.Research methods:This clinical observation adopts the method of random control design,selects the case data of 60 insomnia patients,and divides into the treatment group and the control group,each group is 30 cases,the treatment intervention of the treatment group is Nourishing Yin and clearing heat prescription,the treatment intervention of the control group is estazolam,and the course of treatment of both groups is 4 weeks.Before and after the experiment,the Pittsburgh sleep quality index(PSQI)scale and TCM syndrome score scale were measured and recorded.In this study,SPSS.20.0 was used for statistical analysis to determine the effectiveness of Nourishing Yin and clearing heat prescription in the treatment of insomnia of liver and kidney yin deficiency type.All the statistical tests were bilateral tests,P<0.05 was statistically significant,P<0.01 was statistically significant.Results:1.The general situation comparison in this study is to compare the age and gender of the two groups,showing no statistical significance(P>0.05),and to compare the PSQI score and TCM syndrome score of the two groups before medication,showing no statistical significance(P>0.05),the two groups have comparability.2.After 4 weeks of treatment,the Pittsburgh sleep quality index(PSQI)scores of the two groups before and after treatment were statistically analyzed.The total score and items of PSQI before and after treatment in the treatment group were compared(P<0.05).Compared with the control group before and after the treatment of PSQI items and total score,P<0.05,there was statistical difference.There was no statistical difference between the treatment group and the control group in terms of PSQI items and total scores(P>0.05).Pittsburgh sleep quality index as the scoring standard,there was no difference between the two groups.3.After 4 weeks of treatment,the TCM syndrome scores of the two groups before and after treatment were statistically analyzed.Compared with the treatment group before and after the treatment of TCM syndrome items and total score,P<0.05,there was statistical difference.Compared with the control group before and after treatment of TCM syndrome items and total scores,compared with insomnia and total scores,both showed P<0.05,there was statistical difference;compared with the waist and knee soft,hot and night sweats,five heart fidgety heat,dry throat less fluid,irritability,dizziness and tinnitus,7 showed P>0.05,no statistical difference.Compared the items and total scores of TCM syndromes in the treatment group and the control group after treatment,there was no statistical difference in insomnia(P>0.05);compared with waist and knee tenderness,hot flashes and night sweats,five heart trouble and heat,pharyngeal dryness and little body fluid,irritability and irritability,dizziness,tinnitus and total scores,8 items showed P<0.05,with statistical difference.The therapeutic effect of the treatment group was better than that of the control group4.In the evaluation of clinical efficacy,the reduction rate of Pittsburgh sleep quality index scale was used as the efficacy evaluation index.In the treatment group,3 patients were cured,10 patients were effective,13 patients were effective,4 patients were ineffective,the total effective rate was 86.7%;in the control group,2 patients were cured,14 patients were effective,11 patients were effective,3 patients were ineffective,the total effective rate was 90.0%;after statistical analysis,P=0.563>0.05,there was no statistical difference between the two groups,indicating the therapeutic effect of the two groups There was no significant difference in effect.Taking the reduction rate of insomnia syndrome scale of liver and kidney yin deficiency as the evaluation index,the treatment group recovered 5 people,11 effective people,11 effective people,3 ineffective people,the total effective rate was 90.0%;the control group recovered 0 people,2 effective people,6 effective people,22 ineffective people,the total effective rate was 26.7%;after statistical analysis,P=0.000<0.05,there was statistical difference,indicating that there was significant difference in the efficacy of the two groups.Conclusion:1.Nourishing Yin and clearing heat prescription and Estazolam can both improve Pittsburgh sleep quality index of insomnia patients.The two groups have a clear effect,but there is no statistical difference.2.Nourishing Yin and clearing heat can improve the symptoms of TCM syndromes,and the curative effect is clear;Estazolam could only improve 1 symptom of insomnia in TCM syndromes,and the other 7 symptoms were not improved.The curative effect of Nourishing Yin and clearing heat prescription is obviously better than that of Estazolam.