Study On Clincal And Experimental Of Optimized Shuang-Fu-Jin In Treating Acure Eczema By Orthogonal Design Experiment

The thesis include literature sunmmarizing and syudy report tow parts.the literature include three parts.which is western medicine, traditional Chinese medicine(TCM) and the study on traditional Chinese medicine(TCM) compound by orthogonal design experiment. The part of western medicine summarize studing and treating development of eczema recently in epidemiology.etiology.pathogenesis and treatment. The part of TCM review and analyse the cognition of eczema's pathogeny and pathogenesis, basal study and treatment headway, sum up the study actuality of treatment eczema by external using herba portulacae.radix sophorae flavenscentis.cortex phellodendri and radix sanguisorbae.The ihird part sum up detailed measure and superiority in studing TCM compound by orthogonal design experiment.Tutor professor Bai yanping sum up treating eczema experience in western medicine and TCM during long-term clinic practice, invent a kind of new type preparation named shuang-fu-jin .which is externally used treating acute eczema and dermatitis. It's rescription has clearing heat and toxic material.dring damp and stopping itching.Experiment study approve the prescription of shuang-fu-jin action which is well contradicting inflammation.astringency.stoping itching and regressing bacteria.Through clinic research,shuang-fu-jin have better curative effect.little side effect and easy to usingThe aim of experiment study optimize the prescription of shuang-fu-jin by orthogonal design experiment, Accoding to edema degree and thickness difference about mouse ear, Accoding as herbs anti-inflammatory avail for acute eczema inflammatory model.analyse those herbs primary and secondary relation .optimizing the prescription.filtrating it's herbs.improving on it's pick-up technics. Experiment study show mostly herb anti-inflammatory contribute of the prescription,that one after another is portulacae, radix sanguisorbae.radix sophorae flavenscentis and cortex phellodendri.The new prescription is portulacae 30 gram, radix sanguisorbae 30 gram, radix sophorae flavenscentis 30 gram.it's best picking-up method one after another is decoction in 70 percent ethanol, decoction in water.decoction in water. Making clear the result of experiment study from it's effective scomponent.physical and chemic character and pharmacody function.The new prescription have better anti- inflammation function.The aim of clinical study is validating the curative effect and safety of the new prescription treating acute eczema.According as acute eczema diagnoses standard from Clinical Dematology, According to acute eczema grade and curative effect standard from New Chinese Traditional Medicine Clinical Rudder.comparing with the primary prescription and physiological saline.The result show good effect in the new prescription group and the primary prescription group.those tow groups both have better effect than physiological saline group. Though cure rate and total efficiency rate in the new prescription group both higher than in the primary prescription group.but compare with the tow groups.there isn't statistics difference.ln the end of period of treatment,...