Research On Correlation Between TCM Syndrome Differentiation Of Obstructive Sleep Apnea-hypopnea Syndrome And Polysomnography

Objective:Observe and study the correlation between TCM syndrome differentiation of obstructive sleep apnea-hypopnea syndrome and polysomnography indicators,explore new approaches to quantify objective indicators and future guide clinical diagnosis treatment by carrying on TCM syndrome differentiation to polysomnography-confirmed sleep apnea-hypopnea syndrome.Methods:From January 2008 to January 2009,We collected 200 cases met the standard of inclusion criteria of obstructive sleep apnea-hypopnea syndrome among patients with snoring at PSG monitoring rooms of my branch that carrying on polysomnography checking,divided them into four symptom types according to TCM syndrome differentiation: colorectal throat phlegm type;dampness endogenous type;phlegm and blood stasis type and deficiency of liver and kidney type;recorded gender,age,height,weight,neck circumference, body mass index,sleep stages,respiratory disturbance index,total apnea time,the longest apnea,oxygen saturation,SaO₂＜90%time of all the patients;analyzed correlations between indicators of different TCM syndrome with polysomnography through SPSS 13.0.Results:1.There are obvious inter-group difference between different TCM syndrome of OSAHS in Age,BMI,neck circumference,AHI,total apnea time,the longest apnea time, LSaO₂ and SaO₂＜90%time,suggesting that PSG indicator has guiding significance for TCM syndrome differentiation.2.Age distribution of deficiency of liver and kidney type is significantly higher than the other three types(P＜0.05),phlegm and blood stasis type is higher than colorectal throat phlegm type and dampness endogenous type,suggesting that deficiency of liver and kidney emphasis on the elderly,and phlegm and blood stasis type focused on the middle-aged.3.BMI and neck circumference of dampness endogenous type and phlegm and blood stasis type are significantly higher than colorectal throat phlegm type and deficiency of liver and kidney type(P＜0.05),suggesting that there is a big proportion of fat people in patients of dampness endogenous type and phlegm and blood stasis type.4.AHI of phlegm and blood stasis type is obviously high compared with other three types(P＜0.05),suggesting that severity extent of the disease on phlegm and blood stasis type is more serious.5.Comparing total apnea time,the longest apnea time,LSaO₂ and SaO₂＜90%time between different TCM syndrome types,phlegm and blood stasis type is obviously higher than the other three types,suggesting that in the apnea-hypopnea level,phlegm and blood stasis type is more prominent.Conclusion:1.PSG indicator of age,BMI,neck circumference,AHI,total apnea time,the longest apnea time,LSaO₂,SaO₂＜90%time have guiding significance in TCM syndrome differentiation.2.OSAHS colorectal throat phlegm type and dampness endogenous type emphasis on young people on the age distribution,phlegm and blood stasis type emphasis on the middle-aged and deficiency of liver and kidney type emphasis on the elderly.3.OSAHS dampness endogenous type and phlegm and blood stasis type emphasis on fat patients,which is with high BMI and neck circumstance.4.OSAHS patients of phlegm and blood stasis type is more serious in severity extent, severity extent of deficiency of liver and kidney type is affected by form of disease onset and onset age.5.OSAHS apnea-hypopnea is most prominent in phlegm and blood stasis type.6.Correlation between OSAHS TCM syndrome differentiation standard and PSG indicators deserves further study.