Myogenic Yuyang Soup Treatment Of Liver And Stomach Qi Stagnation Gastric Ulcers And Helicobacter Pylori Inhibition

Objective:Through the observation of myogenic Yuyang Decoction on liver qi stagnation type gastric ulcer patients and to explore the role of Helicobacter pylori, myogenic Yuyangtang in mechanism of action for the treatment of gastric ulcer, widen train of thought and confirmed the myogenic Yuyang Decoction on Helicobacter pylori inhibition.Methods:一、Clinical research1、February2011to August2011were64patients in the first hospital in Wuhan, Hubei TCM stomach specialist outpatient cases will meet the conditions of gastric ulcer is a Liver and Stomach Qi stagnation patients by randomized controlled method will be testedratio of1:1,32cases were randomly divided into treatment group and control group of32cases. The two groups of patients with was no significant difference in age, gender, disease duration, disease, and comparable (P>0.05).2、The control group to give oral omeprazole capsule,1times a day,1tablets each time,20mg/plate,4weeks treatment. The treatment group take traditional Chinese medicine decoction, myogenic Yuyang soup (Astragalus root, rhubarb,30g10g30g,30g dandelion Hedyotis diffusa, cuttlefish bone, likel5g,20g of three seven lOg). Methods:1doses of medication/day, taking two hours, in strict accordance with the traditional Chinese medicine decocting method taking medicine juice400ml, respectively, in the morning and evening after meal1hours of warm. The course was4weeks. All patients during treatment without the use of other antibiotics or other drugs in the treatment of this disease. Patients during treatment and Feigan thick and greasy and spicy cold products.3, Statistical analysis methods:all measurement data using X+S (mean+/-SD) said, were compared between groups using t test, count data using X2test, rank data using Ridit analysis, using SPSS18.0statistical software for data analysis.software for analysis二、Bacteria testlml myogenic Yuyang Tang of the stock solution with sterile normal saline dozens of different concentrations of liquid-fold dilution dubbed, respectively,10ml into the test tube added to the media, inoculating loop to take Helicobacter pylori evenly applied on themicro-aerobic conditions at37℃in culture for72h, the highest dilution factor and the plate no colony forming, its concentration is the MIC.Results:一、 Clinical research1、30cases in the treatment group, the clinical cure in6cases, effective in14cases, effective in6cases, ineffective in4cases, the total effective rate was86.6%; the control group of30cases, the clinical cure in5cases, effective in16cases, effective in3cases, ineffective in6cases, the total effective rate was80%. Comparison of curative effect of two groups total efficiency of no significant difference (P>0.05). Two groups of cases in the course of treatment showed no obvious adverse reaction.2、The main symptom improvement after treatment in the treatment group than the control group (P<0.05).3、The endoscopic healing rates after treatment in the treatment group than the control group (P<0.05).4. Hp clearance rate after treatment, the treatment group than the control group (P<0.05).二、Bacteria testThe myogenic ulcers more soup:inhibitory effect on the role of Hp in vitro antibacterial minimum inhibitory concentration MIC value one sixty-four.Conclusion:This research suggest that myogenic Yuyang Decoction is the prescription of effective treatment of liver and stomach qi stagnation gastric ulcer, and in improving clinical symptoms, endoscopic ulcer healing rate and inhibit the the Hp terms of the only western group; myogenic Yuyang Tang in vitroHp inhibition. And myogenic Yuyang Tang reducing GU relapse and medication adverse reactions to further promote the use of simple western medicine group, it is worth.