Quality Evaluation System Of Alternanthera Philoxeroides Antiviraleffective Fractions Of The Extract

Alternanthera philoxeroides [Alternanthera Alternanthera (Mart.) Griseb] is Amaranthaceae Alternanthera (Amaranthaceae)(Alternanthera) perennial herb, with clearing and detoxifying, cooling blood and diuretic efficacy. Previous researchers of chemical composition, pharmacological effects and clinical applications, of Alternanthera philoxeroides demonstrated that Alternanthera philoxeroides with antiviral efficacy for the treatment of viral diseases.Experimental preliminary studies show that Alternanthera philoxeroides contained flavonoids, saponins and other components and they have antiviral activity.On this basis, the lab implemented reserch with Wuhan Hvsen Biotechology Co.LTD,intends to develop Alternanthera philoxeroides effective substance fractions extract to the traditional Chinese veterinary new drugs.In order to ensure the quality of the extracts of Alternanthera philoxeroides.This paper establish the quality evaluation system of the effective fractions of the extract.Use of modern analytical techniques, we study such as the traits、the TLC identification、the limited check (heavy metals、arsenic salts、macroporous resin residues) and determination of the effective fractions of extracts of Alternanthera philoxeroides, developed a moreimprove quality standards. Established a variety of active ingredient content determination methods which with good reproducibility and reliability. It Can effectively control the quality of the effective substance fractions of extracts. HPLC method was used to develop the fingerprint of the effective parts of Alternanthera philoxeroides group extracts. Reproducibility and stability of the determination of peak legible similarity, in line with the State Food and Drug Administration promulgated "fingerprint of traditional Chinese medicine injection technology requirements (Interim) requirements for Alternanthera philoxeroides the quality evaluation of the grass effective fractions of extracts provide reliably basis.Quality standards and the fingerprint of the effective fractions of extracts of Alternanthera philoxeroides combination of build quality evaluation system for the effective parts of Alternanthera philoxeroides group extracts, so as to Alternanthera philoxeroides further development of Chinese medicine injection of veterinary drugs intermediates with international standards of quality evaluation methods.