Older Men With Chronic Obstructive Pulmonary Disease Stabilization Deficiency Syndrome And Bone Mineral Density Of The Correlation Research

Objective:This paper studies on the dependablity between syndrome of qi-deficiency in gerontal male chronic obstructive pulmonary disease (COPD) and bone mineral density(BMD) from the theory and clinical research, it was likely to provide the basis for dialectical treatment and prevention of complications.Methods:According to the inclusion criteria and exclusion criteria,42cases with gerontal male chronic obstructive pulmonary disease of qi-deficiency who had been to the affiliated department of respiration of Wangjing Hospital of CACMS between Mar.2012to Feb.2013were chose. We have cleared disease grades and the different traditional chinese medicine (TCM) syndrome type by recording their basic information, medical history, lung function, blood gas analysis,and measured their bone mineral density of femur(bilateral all)、lumbar vertebrae2-4by us ing Lunar dual X-ray absorpt iome try OXA). Then all data were processed with SPSS16.0to counted old male COPD patients decreased bone density、 osteoporosis rate, and studies the effect of increased smoking index、 GC cumulabt、hypoxemia、hypercapnia and the degree of airflow limitation to bone mineral density.Based on the TCM syndrome differentiation standard,patients in the group were divided into qi-deficiency group of both lung and spleen, qi-deficiency group of both lung and kidney to compare the difference of bone mineral density,and studied the correlation of qi-deficiency and bone mineral density.Results:In this study, all cases of low bone mass detectablerate and osteoporosis detectablerate is26.19%and23.81%on the lumbar vertebrae2-4,52.83%and16.67%on the femur; The BMD in COPD patients of qi-deficiency group of lung and kidney was lower than that in those of qi-deficiency group of both lung and spleen, there was significant difference between two groups of Statistics (p<0.05), syndrome of kidney qi-deficiency and decreased bone density in lumbar were high correlation(p<0.01);The BMD in the group whose smok ing index more than900was depressed than the group whose smoking index less than900, there was significant difference between two groups of Statistics (p<0.05); The BMD of long-term inhaled glucocorticoid group was decreased than the group of short-term inhaled corticosteroids, there was not significant difference between two groups of Statistics (p>0.05); The BMD of hypoxemia group was decreased than the group of non-hypoxemia group, there was not significant difference between two groups of Statistics (p>0.05); The BMD of hypercapnia group was decreased than non-hypercaPnia group, there was not significant difference between two groups of Statistics (p>0.05); With the degree of airflow limitation gradually Increase, bone mineral density showed a downward trend. Moderate, severe groups bone mineral density compared with the mild group respectively, there was significant difference between two groups of Statistics (p<0.05), but there was not significant difference between two groups Statistics of moderate and severe (p>0.05).Conclusion:Through the study on the qi-deficiency Syndrome and bone mineral density of elderly male patients with stable COPD, we had found that there was a high correlation between kidney qi-deficiency and bone density reduced,we could speculate it may have a preventive effect on the occurrence of osteoporosis in patients with COPD to give tonifying kidney treatment intervention timely on the kidney qi-deficiency in patients with COPD. In this study, all cases of low bone mass detectablerate was consistent with literature reports, but osteoporosis detectablerate was not; Elderly male patients with COPD os-Teoporosis predilection sites may be in the femur. COPD combined with osteoporosis was the result of a combination of factors, especially higher smoking index、severity of airflow limitation were more obvious impact.