| Objective Chronic colitis is a non-Crohn’s disease (CD) in inflammatory bowel disease. Typical performance for abdominal pain, diarrhea, stool with mucus and even blood and pus, Te nesmus or different degrees of systemic symptoms, only a s mall number of patients with constipation without bloody stoo ls, Which is haracterized by recurrent, delayed healing, can cer may be present in patients with evere possible, to the quality of life of patients have serious repercussions, an d in recent years, the incidence has increased year by year, Modern medicine for the disease etiology, pathogenesis has not been studied well, drugs and methods of treatment are q uite scarce, Most uses of 5-amino salicylic acid, cortico steroids, antibiotics, very few will be used in patients wit h severe immunosuppression or surgery, There is a considerab le proportion of patients significant discomfort and side e ffects, Recent clinical study clinicians began to seek more and more Chinese medicine treatment methods, including the use of enema treatment of chronic colitis get a lot of reco gnition, But TCM prescriptions kept flexible, there is n o uniform diagnostic and treatment standards. For this stud y, chronic colitis heat herbal decoction combined with g entamicin,dexamethasone enema approach and explore the feasi bility of implementing thesecond method, the clinical effec t and have the advantage, for clinical practice law and pro vide the necessary basis for further improvement.Methods 94 patients (male 56 cases, female 38 cases) d iagnosed with chronic colitis Damp-heat Syndrome divided in to a treatment group and a control group, the treatment grou p of 48patients, including 30 males and 18 females,46 case s in the control group, which 26 males and 20 females, Afte r statistical analysis, patient groups were not significa ntly different (p> 0.05) in age,gender, disease duration, muc osal lesions and disease stage, comparable. The treatmen t group received saline 9 gentamicin 70ml with 4ml (1 6 million units) and dexamethasone lml (2.5mg) retention en ema once daily at 10:00 am, prescriptionmedicine Kushen 1 5g, Huangbo 15g, Baizhi 15g, Yejuhua 15g, Wubeizi 15g,We ilingxian 15g, Danpi 15g, Chishao 15g, each Decoction 20 0ml,100ml bag-packing, every night 20:00 enema bag,12 days for a course of treatment; The control group receive d saline 70ml with gentamicin 4ml (16 million units) and dexame thasone 1ml (2.5mg) retention enema once daily at 10:00 am,20:00 enema every night, the same as 12 days fo r a course of treatment, Adopt the provisions of the standa rd method, after a course of treatment were compared usin g statistical methods in signs and symptoms, mucosal change the situation on the differences in overall efficacy endpo int.Results After a course of treatment, the statistical ana lysis software SPSS19, symptom scores compare two sets of o bjects P<0.05, the difference was statistically significant, suggesting a course of treatment, the treatment group in i mproving the symptoms of Chinese medicine is superior to th e control group; Endoscopic mucosal grading comparison P<0. 05, the difference was statistically significant, suggestin g a course of treatment, the degree of improvement in endo scopic mucosal better treatment group and the control group; Treatment group were cured,30 cases,12 cases markedly ef fective in 4 cases, the total effective rate was 95.83% in the control group were cured,18 cases,10 cases markedly e ffective in 14 cases, total effective rate was 91.30%, P<0. 05, the difference was statistically significance; Before tr eatment, comparing two groups of objects integral P> 0.0 5, not statistically significant, suggesting that the two gro ups were comparable data, the treatment group and the contro 1 group before and after treatment were done comparing the integral, and its p-value less than 0.05, suggesting tha t after treatment, the patient’s symptom sare improved, the re is a certain treatment, after treatment, both groups int egral comparison P<0.05, the difference was statistically si gnificant, suggesting that the treatment group method is sup erior to the control group.Conclusion This study was based on the basis of traditio nal Chinese medicine, give full play to the advantages of tr aditional Chinese medicine treatment, the use of Chinese herb al medicine combined with Western medicine concept retentio n enema method of treatingchronic colitis, Especially fo r patients with distal colon, this treatment method is con venient and easy,with a topical, high drug concentration, s ide effects can be avoided oral, reducing the characteristi cs of medicine use At the same time bring superior effects of treatment, seriously explore traditional Chinese medicin e diagnosis and treatment, hair cut herbs diversity, for th e treatment of chronic colitis development has broad prosp ects. |
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