| Objective:To observe the clinical effect of modified huoxue-tongmai Decoction combined with conventional western medicine for chronic Coronary heart disease angina pectoris and to explore its mechanism.Methods:76 cases of blood stasis resistance syndrome in patients with stable angina inclusion and exclusion criteria were collected from the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, diagnosed and admitted for treatment, were randomly divided into a control group of 38 patients, the group of 38 patients was observed. The control group received conventional western medicine, the observation group were treated with conventional western medicine and huoxue-tongmai Decoction, for 4 weeks. Observe the Efficacy of angina pectoris, TCM symptoms Efficacy, ECG Efficacy after treatment. Observe the frequency and duration of angina pectoris, and nitroglycerin stopped reduction. Using statistical software SPSS 20.0 statistical analysis, P<0.05 to have significance.Results:In angina pectoris curative effect, the total effective rate of observation group was 84.21%, the control group was 50.00%, the two groups have a significant difference (P<0.05); In improving TCM symptoms, the improvement of angina pectoris attack frequency and duration,the observation group is better than that of control group (P<0.05); In improving electrocardiogram and nitroglycerin stopped reduction, observation group is better than that of control group (P< 0.05). The two groups of patients showed no abnormality in the blood,liver and kidney function tests have no obvious abnormalities before and after treatment.Conclusion:huoxue-tongmai Decoction combined with conventional western medicine treatment of coronary heart disease with stable angina can improve efficacy, improve the clinical symptoms, security. Its mechanism of action may be related to outspread heart coronary artery, against myocardial ischemia and inhibit platelet aggregation, improve microcirculation, regulate blood lipids are many factors, such as worthy of further in-depth study. |
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