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Study On Clinical Incidence And Intervention Therapy Of Cystitis Glandularis In Several Hospitals’ Outpatients Of Suzhou

Posted on:2018-02-17Degree:MasterType:Thesis
Country:ChinaCandidate:Q GuFull Text:PDF
GTID:2334330542967392Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective:1.Preliminary assessment for the clinical situation of Cystitis Glandularis(CG)in the hospital of Suzhou area,the improvement for check-out rate about cystitis glandularishas induced with Lower urinary tract symptoms(LUTS),while to further improve cognitive degrees for clinical situation of cystitis glandularishas induced with LUTS by urinary surgical doctor,and analysis the achievement from academic research aspects of epidemic,for providing epidemic learn bases of clinical diagnosis and treatment for cystitis glandularishas,for exploring the way of effective diagnosis and treatment.2.To diagnose patients for the treatment of transurethral resection of epirubicin hydrochloride,or added transurethral bladder perfusion,and observation of patients with physiological and psychological after operation,comparing the treatment of efficacy and safety between two methods.Explore transurethral resection or transurethral resection combined with EADM therapy in the prevention of postoperative recurrence of clinical effect for clinical diagnosis and treatment of cystitis glandularis certain basis.Method:1.During January,2015 to December,2016,the patients suffered from cystitis glandularis in two large integrated third-grade class-A hospital in Suzhou area(The First Affiurted Hospital of Soochow University and Suzhou Kowloon Hospital Shanghai Jiao Tong University School of Medicine)were set by the basic crowd,and the database were established by these patients,and statistics analysis the related factors occurred with cystitis glandularis;Using diagnostic criteria of cystitis glandularis,pathological observation,cystoscopy and biopsy of the bladder mucosa random check,and confirming the treatment of cystitis glandularis.2.Confirmed the diagnosis database of 186 patients by pathological for cystitis glandularis and give consent to surgical treatment in hospital,the follow-up 146 patients were get at least for 24 months(18 patients non-contacted),51 patients were treated by pure electric resection;and another 95 patients were treated by transurethral electric resection combined epirubicin hydrochloride;All cystitis glandularis patients were admitted to hospital and 24 months after the review of Self-rating Anxiety Scale(SAS)and Quality of life(QOL)score data[1],the analysis of the above cases related to clinical data,and the cure rate,the recovery,the recurrence rate,inefficient and treat anxiety score,quality of life index difference of simple cutting and cutting joint epirubicin hydrochloride new perfusion group of patients were analysized by using of statistical methods.Result:1.In 186 patients admitted to hospital,the male proportion were accounted for 24.5%,female for 75.5%;More people focus on the 21-30 years old and 31-40 years old,accounted for 22.4%and 24.5%,respectively.the average age was 42.1 years old;About profession with patients,the proportion of workers is the largest,were 41.5%;In terms of education level,the junior middle school students and the degree of patients account for nearly half proportion(51.3%).The population suffered from cystitis glandularis may be related with the life habits of eating excitant food and a full bladder.2.Patients suffered from glandular cystitis were treated by random cystoscopy and bladder mucosa biopsy,pathological observation,such as inspection,found that the diseased tissue,diagnose bladder triangle.3.The stutation of 146 cystitis glandularis patients follow-up in 24 months:pure transurethral resection group,a total of 51 cases,28 cases cured 24 months postoperatively,improvement in 14 cases,6 cases of recurrence,invalid or aggravating 3 cases,cancerous 0cases,effective rate was 82.41%,no efficiency is 17.59%;transurethral resection combined with postoperative bladder instillation group were 95 cases,and 54 cases were cured,26were better,10 cases of recurrence,invalid or increase in 5 cases,cancerous 0 cases,effective rate was 84.26%,15.74%recurrence and inefficient.The effect comparison between two groups was no significant difference(P>0.05).4.Before the treatment,the patients of two groups with SAS and QOL score was no significant difference(P>0.05),but the difference between the patients of two groups with SAS and QOL score was significant after 24 months(P<0.05);the difference surgery compared with after 24 months SAS and QOL scores have obvious in pure transurethral resection group(P<0.05);transurethral resection combined with postoperative bladder instillation group of 24 months after surgery and SAS score on admission to hospital show significant difference(P<0.05),and QOL contrast has no obvious difference(P>0.05).Conclusion:1.Frequent cystitis glandularis in women,especially to eat excitant food and have a full bladder and other bad habits may increase the risk of the disease.Cystoscopy and bladder mucosa biopsy and auxiliary pathological observation are confirmed cystitis glandularis preferred check method.2.Transurethral resection combined with postoperative bladder instillation is no more than pure transurethral resection in treatment of glandular cystitis for better short-term curative effect;Treatment of transurethral resection combined with postoperative bladder instillation in glandular cystitis could increase the patient’s anxiety and may lower the quality of life;For poor after treatment with anti-inflammatory effect of glandular cystitis patients,considering to choose treatment of pure transurethral resection was more better.
Keywords/Search Tags:Cystitis glandularis, Epirubicin Hydrochloride, Self-rating Anxiety Scale, Lower urinary tract symptoms, Instillation of bladder, Quality of life
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