A Comparative Study Of Pure Transurethral Resection And Transurethral Resection Combined With Postoperative Bladder Instillation Of Cystitis Glandularis

Objective To study and discuss about significance about the postoperative bladder instillation of cystitis glandularis,and to improve the level of recognition and treatment about cystitis glandularis.Methods we collect the datas of these cases who were diagnosed as cystitis glandularis by pathological examination and were admitted to hospital for surgery in the first people’s hospital of Yueyang city (Yueyang people’s hospital affiliated to central south university) from july2007to march september2012,and61of those were followed up for more than one year.37cases were processed by pure bipolar transurethral plasma kinetic resection,while24cases were processed by bipolar transurethral plasma kinetic resection combined with postoperative instillation of mitomycin.We have analyzed the clinical datas of these cases and compare the rate of cure,the rate of improvement,the rate of recurrence,the rate of inefficiency,self-rating anxiety scale(SAS)and quality of life(QOL) by statistical methods.Result The follow-up results at fist12months after surgery about the61cases who were diagnosed as cystitis glandularis are as follow:37cases were in the group of pure bipolar transurethral plasma kinetic resection(TUPKR) and23cases were cured,7cases were improved,5cases were relapsed,2case was ineffective and no canceration,and the rate of efficiency was81.08%,while the rate of recurrence and inefficiency was18.91%;24cases were in the group of bipolar transurethral plasma kinetic resection(TUPKR)combined with postoperative instillation of mitomycin and15cases were cured,5cases were improved,3cases were relapsed,1case was ineffective and no canceration, and the rate of efficiency was83.33%,while the rate of recurrence and inefficiency was16.67%; The postoperative efficacy between the three groups was not statistically significant(P>0.05);the self-rating anxiety scale(SAS) and the qualtiy of life(QOL) index before operation have no statistical difference between the three groups(P>0.05),while the SAS and the QOL index were statistically different between the pure TUPKR and the TUPKR combined with bladder instillation in12months after surgery(P<0.05);there were no statistical difference about SAS and QOL between preoperative evaluation and postoperative evaluation in the pure TUPKR(P>0.05),while there were significant statistical difference about SAS and QOL between preoperative evaluation and postoperative evaluation in the group of TUPKR combined with bladder instillation(P>0.05).Conclusion (1) TUPKR combined with postoperative mitomycin perfusion took no advantage over the pure TUPKR in the postoperative efficacy.(2) TUPKR combined with postoperative mitomycin perfusion in the treatment of cystitis glandularis may increase patient anxiety(SAS)and quality of life index(QOL).(3)For those cases who live with reduplicated symptoms after anti inflammation treatment,pure TUPKR is a reliable choice.