Analysis Of Clinical Features In Different Aged Male Patients With Non-ST-segment Elevation Acute Myocardial Infarction

Objective: According to the domestic reports in the literature,in recent years the incidence of NSTEMI has increased year by year,and it has the characteristics of low survival rate,poor prognosis in Mid-long term atypical ECG changes,it has become the hot and difficult point in the research of cardiovascular disease.And NSTEMI occurred more frequently in the elderly,but in recent years,with the change of the diet structure and living habits,especially the work pressure increases,the pace of life and other factors,The age of onset of NSTEMI is earlier and younger.It is recognized in the medical community that the estrogen has a protective effects on vascular endothelial.This study exclude gender influence of NSTEMI,by comparing the case of young and middle-aged male patients and elderly male patients who have NSTEMI,analyzing the characteristic between the two groups,then provide certain reference basis clinical diagnosis,treatment and prevention of this disease,which allow clinicians to diagnosis quickly and accurate of NSTEMI,then make a more scientific and reasonable treatment.Methods: Selected male patients with NSTEMI during Jan.2015 to Dec.2015,from the First Hospital of Jilin University.They were divided into two groups according to the age: under the age of 60 is the group of young and middle-aged;60 years old(including 60)is the group of elderly.There were retrospectively analyzed for the elements of the cases of above two groups,including age,smoking history,drinking history,family history,diabetes history,history of hypertension,hyperlipidemia,blood pressure,lesion blood vessel number,the changes in myocardial enzyme,the triggers,starting symptoms,hospitalization days,serum potassium,serum sodium,cholesterol,blood platelet count and blood coagulation routine.In this study,the data of metering with average data ± standard deviation(X±s)present,count data expressed in percentage(%),uses the independent sample t-test to compare differences between the two groups,using chi-square test to compare the count of data between the two groups,P<0.05 that was statistically significant.All data uses SPSS17.0 software for processing.Results: 1.Among the male patients with acute NSTEMI in this research,in comparison with the clinical features of young and middle-aged and elderly group,the statistically significant factors include:diastolic blood pressure,pulse pressure,total cholesterol,triglyceride,low density lipoprotein,apolipoprotein B,the average blood protein concentration,creatinine,RBC,hemoglobin,red blood cells deposited,red blood cell distribution width and platelet distribution width,platelet deposited,platelets,plasma fibrinogen,prothrombin time,prothrombin activity,the triggers,main symptom,cardiac function,imaging and support situation,the number of lesion vessels;And found no significant statistical difference in history of hypertension,diabetes,hyperlipidemia,history,history of drinking,systolic blood pressure,heart rate,high density lipoprotein,apolipoprotein A1,CK-MB,serum sodium,potassium,glucose,hospitalization days,total bilirubin,direct bilirubin,indirect bilirubin,total bile acid,heart palpitations troponin I,white blood cells and so on.2.This study found that in male patients with NSTEMI group,family history of young and middle-aged group was obviously higher than that of the elderly group.This suggests that the young and middle-aged male patients with NSTEMI group is more susceptible to genetic factors than elderly group.There were 5 cases(2.7%)of family history of coronary heart disease in young and middle-aged men group,and 1 case(0.3%)in the elderly group,by chi-square test(P<0.05).3.In terms of blood pressure,the systolic blood pressure between the two groups had no statistical difference,but there was a statistically significant difference in diastolic blood pressure and pulse pressure.4.Through the study we found that a number of indicators of lipid in young and middle-aged group were higher than elderly group,and statistical tests showed that the difference was obvious.5.In the case of blood,on the red blood cell,PDW、PCT、PLT and MCHC,there were significant differences between the two groups.6.In terms of blood coagulation routine,through comparation of plasma fibrinogen and PTA,there was significant difference between the two groups.Conclusion:1.Among male patients with NSTEMI,compared with two different age groups(young and middle-aged and elderly),diastolic blood pressure and pulse pressure of young middle-aged group are generally higher than elderly group.2.Compared with two groups,they had differences in blood routine,coagulation convention and so on.3.For NSTEMI caused by cold,elderly group had a higher morbidity than young and middle-aged group.