| Objective:Carding research on the pathogenesis of forgetfulness before Tang and Data Mining on the Relevant Application Laws of Forgetful Treatments before Tang Dynasty.Methods:In the Aspect of Etiology and pathogenesis:By searching the relevant ancient books before Tang Dynasty(excluding the meridians of acupuncture and moxibustion books)in the General Catalogue of Ancient Books of Chinese Traditional Medicine,we can conclude the Target ancient books.Then,records the Relevan Discussion of forgetfulness in the paper of the literature included above,and Discusses the related Disease name、etiology and pathogenesis through Using the methods of literature analysis、comparative analysis Mathematical Statistics.The issues related to Prescriptions:Research the related problems of prescriptions in the relevant chapters of literature research,use EXCLE software to understand The related problems of prescription through the method of mathematical statistics.and The association analysis of couplet medicines was carried out by Apriori algorithmResults:In the study of etiology and pathogenesis:11 ancient books were included:The Yellow Emperor’s Internal Classic、Shanghan Zabing Lun、Beiji Qian jin Yao Fang、Essential Secrets from Outside the Metropolis、General Treatise on the Cause and Symptoms of Diseases、Hai Shang Fang、Su Wen Secret Words、Fahrenheit Zhongzang Jing、Picture of Huatuo Xuanmen、Handbook of Prescription for Emergency、Supplement to Thousand Golden Prescriptions.Studying the discussion of forgetfulness in the above books leads to the following conclusions:1.There are 20 different disease names,and mainly they are in the book of Yellow Emperor’s Internal Classics,Beiji Qianjin Yao Fang,Supplement to Thousand Golden Prescriptions,Essential Secrets from Outside the Metropolis,General Treatise on the Cause and Symptoms of Diseases 2.the etiology and pathogenesis of Before the Tang Dynasty were complex.Generally speaking,it was thought that the disease of asthenia syndrome is more than excessive syndrome.It involves five Zang-organs and six organs and five elements’ motion and six kinds of natural factors.In part,it was previously believed that the heart and kidney were the key to the disease from differentiation of Zang and Fu.From the point of view of the five elements’motion and six kinds of natural factors,it should be paid Special attention to the damage to Yang Qi caused by Tai Yang Han shui si Tian.and it Emphasized the Viewpoint of Wind evil enters because of asthenia syndrome.3.In the past,there were some Inconsistent Statements between etiology,pathogenesis and prescriptions in amnesia.4.Forgetfulness can exist as a complication of other diseases.In terms of prescriptions related issues discussed:Research on some related problems of prescriptions in literature research above,So we studied the 91 prescriptions.1.it found these prescription are distributed in five books including Qian Jin Yao Fang、Qian jin Yi Fang、Treatise on Cold Pathogenic and Miscellaneous Diseases、Hai Shang Fang、Essential Secrets from Outside the Metropolis according to Statistics on the distribution of these prescriptions in these books.According to the analysis of frequency and other data,we found that there were 159 Chinese medicines in the 91 prescriptions,Among them,81 traditional Chinese Medicine were found in the first 90%of them.The top six drugs are very similar to Dingzhi Xiaowan.2.Analysis of the channel tropismthe heart channel ranked first in 349 times followed is the the spleen channel 254 times.3.According to the classification of traditional Chinese medicines,the top five medicines were Deficiency-nourishing drugs、the drug can dispel the wind,diuresis-promoting herbal medicine,heat-clearing drug,drugs for dispelling internal cold.4.According to the classification of the quantity of traditional Chinese medicine in these prescriptions,the most common prescription was Siweifang(13.19%)and The proportion of prescriptions less than 13 flavors was 82.42%.5.According to the natural attributes of drug use,123 kind of drugs belong to plants in 159 drugs,accounting for 0.7736.6.Analysis the four properties and five tastes of the first 90%drugs used in 91 prescriptions.the use of Warm drug ranks first In the part of four properties.Analysis of the five tastes:sweet drugs is the most used.7.Classification of drug formulations:Among the seven formulations,decoction was widely used in the past,but solid formulations were the most widely used.8.The analysis of additives in prescriptions showed that there were 7 types of additives,among which alcohol and medicine were more frequently used.9.it was found that the application of wine blending in pill powder was more common used through the analysis of the prescriptions added wine.10.the spleen channel and the heart channel are more common According to the theory of meridian tropism.11.By calculating the contraindication of the prescription with EXCLE software,20 kinds of contraindication drugs were found in the treatment of amnesia,among which lettuce,oxalis,seaweed,custard,garlie and pork ranked the top six. Association analysis of the Amnesia related prescription by Apriori algorithm using SPSS software.1.A total of 33 association rules between drug pairs and drug groups were found.2.The common medicines for amnesia are mainly composed of 9 kinds of medicines,including Acorus gramineus Soland.,polygala root,Poria cocos,Ginseng,cassia twig,liquorice,rhizoma zingiberis,angelica,the root of fangfeng.Among them,Poria cocos,Ginseng,cassia twig and liquorice are the four core compatible medicines.Conclusion:the study of the causes and pathogenesis of amnesia Before Tang Dynastyrelated prescriptions and medicines can help us understand the complexity of amnesia and the treatmentdetails. |