| Objective:In this study,the clinical effect of plum blossom needle combined with cupping on postherpetic neuralgia(qi stagnation and blood stasis type)was observed to verify the effectiveness and safety of plum blossom needle combined with cupping.Compared with the oral western medicine gabapentin capsule combined with Mecobalamin dispersible tablets,the effect of plum blossom needle combined with cupping and oral western medicine on postherpetic neuralgia was analyzed and compared The difference of curative effect,advantages and disadvantages can provide a more effective,safe and economic treatment plan for clinical treatment of the disease,and guide clinical work better.Methods: From May 2018 to may 2019,60 patients with postherpetic neuralgia who met the inclusion criteria were selected from the Acupuncture Department of Guanggu Hospital of Hubei Province.The patients were divided into plum blossom needle combined with cupping group(combination of needle and cupping group)and oral gabapentin capsule combined with Mecobalamin dispersible tablets group(Western medicine group).In the acupuncture and cupping group,plum blossom needle combined with cupping method was used:(1)plum blossom needle percussion: the plum blossom needle was used to percussion the corresponding spinal cord segment along the governor vein and the distribution area of herpes zoster by light and medium means,with the skin slightly red as the degree,without puncturing the skin;(2)puncture and cupping: the plum blossom needle was used to percussion at Ashi point with heavy means,and then cupping was performed after bleeding,with no more than 4 canisters at a time.Plum blossom needle percussion once a day,puncture and cupping once every three days,every 6 days,rest for one day,2 weeks as a course of treatment,a total of 2 courses of treatment.Western medicine group was treated with oral gabapentin capsule and Mecobalamin dispersible tablets: Gabapentin capsule: the first day dose was 0.1g/time,3 times / day,the next day increased to 0.2g/time,3 times / day,the third day dose was 0.3g/time,3 times / day,and then maintained the third day dose.Mecobalamin dispersible tablets: 0.5mg/time,3 times / day.Two weeks of treatment is one course,both of them take two courses.The VAS pain score,clinical efficacy,Pittsburgh sleep quality index(PSQI)score and skin disease quality of life index(DLQI)questionnaire before and after treatment were used as the observation indexes for statistical analysis,and the efficacy and safety of plum blossom needle combined with cupping for the treatment of postherpetic neuralgia were evaluated.Results:1.Discontinuation and shedding: during the treatment,1 case in the combination group of acupuncture and cupping,2 cases in the western medicine group,and 57 cases finished the treatment,including 29 cases in the combination group of acupuncture and cupping and 28 cases in the western medicine group.2.Comparison of pain improvement degree between the two groups: after 2 weeks of treatment,VAS score of the two groups decreased significantly after treatment,with statistical significance(P < 0.01).There was no statistical significance between the two groups(P > 0.05),and the effect of acupuncture combined with cupping group was similar to that of Western medicine group;after 4 weeks of treatment,there was statistical significance between the two groups(P < 0.01)The improvement degree of pain in the combination group was better than that in the western medicine group.3.Comparison of the overall clinical efficacy of the two groups: after 4 weeks of treatment,the total effective rate of the combination of acupuncture and cupping group was 93.10%,the total effective rate of the western medicine group was 85.71%,the total effective rate of the combination of acupuncture and cupping group was higher than that of the western medicine group,the difference was statistically significant(P < 0.05).4.Pittsburgh sleep quality index(PSQI)score comparison between the two groups: the PSQI score of the two groups was significantly lower than that before treatment at the two followup visits after two weeks and four weeks(P < 0.01),and the sleep quality of the two groups was improved after treatment;the difference between the two groups was not statistically significant after two weeks of treatment(P > 0.05)After 4 weeks of treatment,there was a significant difference in PSQI scores between the two groups(P < 0.05).The improvement of sleep in acupuncture and cupping group was better than that in western medicine group.5.Comparison of skin disease quality of life index(DLQI)questionnaire survey between the two groups: the DLQI scores of the two groups were significantly lower than those before treatment at the two follow-up visits after 2 weeks and 4 weeks(P < 0.01);there was no significant difference between the two groups(P > 0.05);the quality of life of the two groups was significantly improved after treatment,and the degree was similar.6.No major adverse events occurred in all patients in this study.During the treatment,all patients in the acupuncture and cupping group had no adverse reactions;during the treatment,one patient in the western medicine group had vertigo symptoms,and two patients had sleepiness and fatigue discomfort.The patients were asked to stop taking medicine and drink a proper amount of warm water.After close observation for two hours,the symptoms were relieved and returned to normal.In the later period,there was no adverse reaction and the treatment was completed.Conclusion: Plum blossom needle combined with puncture and cupping can effectively improve the pain symptoms of patients with postherpetic neuralgia of qi stagnation and blood stasis type,improve the quality of sleep and quality of life of patients.Compared with the oral western medicine gabapentin capsule combined with Mecobalamin dispersible tablets,the pain improvement is more significant and the long-term effect is better.In addition,this therapy has no adverse reactions and side effects during the treatment period,which is worthy of clinical application. |
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