Clinical Observation Of Maxing Suqin Decoction In Treating Mycoplasma Pneumonia (Syndrome Of Wind-heat Closing Lung) In Children

Objective: The purpose of this study was to explore the clinical efficacy of Maxing Suqin Decoction combined with azithromycin in the treatment of children with Mycoplasma pneumonia(syndrome of wind-heat closing lung).Methods: In this study,a total of 70 children meeting the criteria were finally included,and randomly divided into the experimental group and the control group,35 cases each.The control group was given azithromycin sequential therapy(intravenous drip for 5 days and withdrawal for 2 days),and the test group was given Ma Xing Su Qin Tang on the basis of control group.Except for antipyretic and antiasthmatic methods for symptomatic treatment,neither group should use any Chinese or Western medicines that may affect the efficacy.The course of treatment in both groups was 7 days.Observe and record the main index scores,secondary disease scores,total scores and individual symptom scores of the children before treatment,after 3 days of treatment and after 7 days of treatment and compare the differences of the two treatments.Result:In this study,a total of 73 children with wind-heat closed lung syndrome of mycoplasma pneumonia meeting the standards were included.During this period,1 child in the test group fell off,because the children did not adhere to take Traditional Chinese medicine.In the control group,2 cases fell off,but dropped out automatically because the parents could not cooperate actively.In the end,a total of 70 children were treated according to the study protocol,with 35 in the experimental group and 35 in the control group.1.General data comparison: there was no statistically significant difference in gender and age distribution between the two groups(P>0.05),indicating comparability.2.Comparison between groups before the treatment:before the treatment therewere nostatistically significan in the main index scores、the score of the second indicators、the total score and the disease distribution(P>0.05)。3.Comparison within the group after the treatment: The scores of fever,cough,appetite and food intake,and tongue symptoms were statistically significant in the test group after 3days of treatment(P<0.05),and the scores of fever and cough symptoms in the control group after 3 days of treatment were statistically significant(P<0.05).After 7 days of treatment,themain index scores,secondary disease scores,total scores,and individual symptom scores of the two groups were statistically significant(P<0.05);in terms of laboratory tests,The number of WBC,N% and L% in both groups had no statistical significance after treatment(P> 0.05),and serum CRP had statisticalsignificance after treatment(P<0.05).4.Comparison between groupsafter the treatment:(1)Comparison after 3 days of treatment: There were unified differences in fever,cough,appetite and tongue image score between the two groups Statistical significance(P<0.05).(2)Comparison after 7 days of treatment:(1)There were statistically significant differences between the two groups in terms of sum of major indicators,sum of minor symptoms and total score(P<0.05).(2)Comparison of single indicators: there were statistically significant differences in fever,cough and sputum score between the two groups(P<0.05).There were statistically significant differences between the two groups in terms of appetite,nausea and vomiting,fever symptoms,and tongue image score(P<0.05).There was no significant difference in the results of laboratory tests between the two groups after 7 days of treatment(P>0.05).(3)Comparison of overall efficacy: the penetrance rate was 94.29% in the experimental group and 85.71% in the control group,the difference was statistically significant(P<0.05).Conclusion: Maxing Suqin Decoction combined with azithromycin in children with mycoplasma pneumonia(wind-heat closed lung syndrome)has a definite effect and is superior to azithromycin treatment alone.The method of combing Chinese and Western medicine treatment can significantly improve the children’s main symptoms such as fever,cough,sputum,etc.And at the same time,it has a great of predominance in improving the children’s appetite,nausea and vomiting.