Based On The Traditional Chinese Medicine Inheritance Auxiliary Platform, Explore The Medication Rules Of Famous And Old Chinese Doctors In The Treatment Of Threatened Abortion

Objective:We aim to collate clinical cases by modern famous Chinese medicine practitioners in particular to treatment for threatened abortion.With the aid of the Traditional Chinese Medicine inheritance platform system software,we would then organize and analyze the relevant information in hope to summaries the clinical syndrome differentiation law by modern famous Traditional Chinese Medicine doctors with regards to the treatment of threatened abortion syndrome.We hope that we can provide a reliable and safe reference for future clinical and scientific research work.Method:We will collate all the relevant prescriptions available using China Knowledge Network,Weipu,Wanfang Database,relevant written books and clinical cases by Traditional Chinese medicine practitioners.We will then use the Traditional Chinese Medicine inheritance platform system software to conclude an association rule analysis or complex system entropy aggregation Class analysis and then combine with current clinical and Traditional Chinese Medicine theory for further analysis and discussion.Results:This study included a total of 173 medical records,191 prescriptions and a total of 154 herbs.The results showed that the most commonly used herbs in the treatment of threatened abortion were mulberry parasitic,white peony,intermittent,dodder silk,glue,Atractylodes macrocephala,Scutellaria baicalensis,Eucommia ulmoides,ramie root and Astragalus membranaceus.These herbs that were used in the treatment of threatened abortion could be classified according to their nature,mainly warm,calm and cold.We found out that sweetness herbs were most commonly used that also belong to the liver,kidney and spleen meridians.Through the analysis of prescription law,the commonly used compatibility of drug pairs are as follow:①Radix Dipsaci,Chinese taxillus herb;②dodder seed,Chinese taxillus herb;③Radix Paeoniae Alba,Chinese taxillus herb;④Colla Corii Asini,Chinese taxillus herb;⑤Radix Dipsaci,Radix Paeoniae Alba;⑥dodder seed,Radix Dipsaci;⑦Rhizoma Atractylodis Macrocephalae,Chinese taxillus herb;⑧Cortex Eucommiae,Chinese taxillus herb;⑨Colla Corii Asini,Radix Dipsaci;⑩Colla Corii Asini,dodder seed.The top ten combination that are oftenly used in TCM prescription are as follow:①dodder seed,Radix Dipsaci→Herba Taxilli(0.90);②Colla Corii Asini,Herba Taxilli→Herba Taxilli(0.86);③Colla Corii Asini,Radix Dipsaci→Herba Taxilli(0.84);④Herba Taxilli→Herba Taxilli(0.83);⑤Radix Dipsaci→Herba Taxilli(0.83);⑥Radix Dipsaci,Radix Paeoniae Alba→Herba Taxilli(0.82);⑦dodder seed,Radix Paeoniae Alba→Herba Taxilli(0.82);⑧Radix Rehmanniae Recens→Radix Paeoniae Alba(0.82);⑨Radix Rehmanniae Recens→Herba Taxilli(0.80);⑩Cortex Eucommiae→Herba Taxilli(0.80)①dodder seed,Radix Dipsaci→Herba Taxilli(0.90);②Colla Corii Asini,Herba Taxilli→Herba Taxilli(0.86);③Colla Corii Asini,Radix Dipsaci→Herba Taxilli(0.84);④Herba Taxilli→Herba Taxilli(0.83);⑤Radix Dipsaci→Herba Taxilli(0.83);⑥Radix Dipsaci,Radix Paeoniae Alba→Herba Taxilli(0.82);⑦dodder seed,Radix Paeoniae Alba→Herba Taxilli(0.82);⑧Radix Rehmanniae Recens→Radix Paeoniae Alba(0.82);⑨Radix Rehmanniae Recens→Herba Taxilli(0.80);⑩Cortex Eucommiae→Herba Taxilli(0.80)Seven New Generations Based on Entropy Clustering Analysis:①Concha Ostreae-Carapax et Plastrum Testudinis-Halloysitum Rubrum-Herba Cirsii;②Pumpkin pedicle-Fructus Rubi-Ootheca Mantidis-Fructus Setariae Germinatus;③Radix Scutellariae-Radix Rehmanniae Recens-Herba Ecliptae-Folium Artemisiae Argyi;④Chinese taxillus herb-dodder seed-Radix Dipsaci-Carapax et Plastrum Testudinis;⑤Radix Angelicae Sinensis-Radix Glycyrrhizae-Rhizoma Dioscoreae-Radix Glycyrrhizae Preparata;⑥Radix Changii-Radix Astragali seu Hedysari-Rhizoma Atractylodis Macrocephalae-OsDraconis-Radix Pseudostellariae-Radix Ophiopogonis-Folium Mori;⑦dodder seed-Radix Changii-Cortex Eucommiae-Radix Astragali seu Hedysari-Radix Pseudostellariae-Radix Ophiopogonis-Fructus Gardeniae-Folium Mori)。Conclusion:The main principle for the treatment of threatened abortion by famous TCM practitioners aligns with ancient treatment theory,mainly by invigorating the kidney and spleen,supplemented by clearing away heat and cooling blood.Afterwhich,each patient will then be treated according to syndrome differentiation,whereby TCM practitioners will adjust their prescription accordingly from the core formula.Those with obvious blood-heat should be treated with Herba Cirsii and Herba Ecliptae to clear heat and cool blood to stop bleeding.Those with heart-kidney incompatibility can be treated with Os Draconis;If both spleen and stomach disharmony occurs,Fructus Setariae Germinatus can be used to invigorate the spleen and stomach;if both stomach yin and stomach yin have heat,Radix Liriopes,Folium Mori,Fructus Gardeniae,and many more can also be used to nourish yin and nourish body fluid,clear away heat and remove boredom.Each formula prescribed clinically is customized specially according to patients’ constitution and clinical symptoms.