Clinical Observation On The Treatment Of Infertility Patients With Non-obese Polycystic Ovary Syndrome By Kidney Nourishing And Liver Clearing Method

Objective:In this study,we observed the clinical efficacy of Kidney-nourishing and liver-clearing in the treatment of infertility patients with non obese polycystic ovary syndrome(PCOS),explore the therapeutic mechanism of Kidney-nourishing and liver-clearing,and to open up a new way of treatment,so as to guide clinical treatment.Methods:A total of 43 patients who met the inclusion criteria and exclusion criteria were collected,23 cases were treated with Kidney-nourishing and liver-clearing prescription combined with letrozole and lifestyle intervention,which was set as the treatment group,and 20 cases were treated with letrozole and lifestyle intervention,which was set as the control group.Observe three menstrual cycles,Record after treatment of ovulation and pregnancy outcomes,and menstrual cycle before and after treatment,kidney liver to improve the situation of syndromes,serum levels of the hormone(LH/FSH,T,E2,SHBG)change,the basal body temperature bipolar curve,through statistical analysis,Objective to evaluate the clinical efficacy of Kidney-nourishing and liver-clearing prescription in the treatment of PCOS infertility patients with kidney deficiency and liver hyperactivity.Results:There were no significant differences in general items before treatment,including age,course of disease,menstrual cycle score,TCM syndrome score,hormone level(LH/FSH,T,E2,SHBG)between the two groups(P>0.05),which was comparable.After treatment:1.Ovulation:the treatment group had 57 cycles of B-ultrasound monitoring,50 of which were ovulation cycles,ovulation rate was 87.72%.And 52cycles were monitored in the control group,36 cycles were ovulation,and the ovulation rate was 70.59%,and the difference between the two groups was statistically significant(P<0.05).2.Pregnancy outcome:the pregnancy rate in the treatment group and the control group was 39.13%and 30%.respectively.The pregnancy rate of the treatment group was better than that of the control group,and the difference was not statistically significant(P<0.05).3.Improvement of menstrual cycle:The menstrual cycle score of the treatment group was lower than that before treatment,and the difference was statistically significant(P<0.05),while that of the control group was not statistically significant(P>0.05).4.kidney deficiency and liver flourishing:the effective rate in the treatment group was 78.26%;The effective rate of the control group was 40%.the effective rate of the treatment group was significantly higher than that of the control group,the difference was statistically significant(P<0.05).5.Hormone levels:In the treatment group,LH/FSH and T values decreased,E2 and SHBG values increased,and the difference was statistically significant before and after treatment(P<0.05);Compared with the control group,the changes of LH/FSH,t and SHBG were statistically significant(P<0.05).6.The basic temperature curve:the biphasic rate of the basic temperature in the treatment group and the control group was 83.61%and 67.86%,respectively.The biphasic rate of the treatment group was higher than that of the control group,the difference was statistically significant(P<0.05).