Xuanshi Pediatrics Study On Data Mining In The Treatment Of Recurrent Respiratory Tract Infection In Children

Objective:To explore the clinical data of "Xuanshi Pediatrics" in the diagnosis and treatment of recurrent respiratory tract infection in non-acute infective period.The analysis included the classification of TCM syndrome types,core drugs,drug classification and drug flavor compatibility.Method:Structured outpatient medical records of children with recurrent respiratory tract infections were established,and relevant factors,syndromes,prescriptions and other information were collected by the outpatient doctor system of Zhejiang Chinese Medical Hospital(Winning Health CIS 5.5)to form the "Xuanshi Pediatrics diagnosis and treatment database" for children with recurrent respiratory tract infections.Later,based on data mining technology,Specifically,it includes frequency analysis,efficacy analysis,association rules and so on to study the experience of Xuanshi Pediatrics in treating children with recurrent respiratory tract infection.Results:1.A total of 102 children with recurrent respiratory tract infection were included in this study,with a male to female ratio of 1.21 to 1.The peak age of onset was(5.50±2.53)years old.The father and/or mother of 72 RRTI children suffered from allergic diseases or had allergic constitution,and there were 64 cases in which the father and/or mother were allergic and their offspring were allergic.The highest proportion of children who preferred meat dishes was 33 cases(32.35%).2.The syndrome type of lung qi deficiency was the common witness type of repeated respiratory tract infection,followed by the syndrome of lung spleen Yin deficiency,lung spleen Yin deficiency combined with lung Qi deficiency and disorder of Ying and wei.3.The commonly used Chinese medicines in the treatment of recurrent respiratory tract infection in the "Xuan’s pediatrics" include Astragalus,Radix glehniae,Adenophora tetraphylla,Radix Scutellariae,Blackberry lily,Oroxylum indicum,Radix Paeoniae Alba,Root-bark of Chinese wolfberry,Flos magnoliae liliflorae,Radix atractylodes,Rhizoma Atractylodis macrocephalae,Ji Neijin,Radix Scutellarice,Tangerine Peel,Zhi Ke,Poria cocos,Medicated Leaven,Cicadae Periostracum and Bombyx Batryticatus.Regarding their nature and flavor,the majority are drugs of bitter taste and cold nature as well as of sweet taste and cold nature.As for their meridian tropism,the most frequently used traditional Chinese medicine are those intended to cure diseases of the lungs,stomach,and spleen.4.Cluster analysis results obtained 4 categories.C1:Radix glehniae,Adenophora tetraphylla Root-bark of Chinese wolfberry,Radix Scutellariae,Blackberry lily,Oroxylum indicum.C2:Astragalus,Chinese yam,Tangerine peel,Radix Paeoniae Alba,Gastrodia,Unguteng,Medicated Leaven,Ji Neijin,Zhi Ke.C3:Parsnips,poria cocos,Rhizoma Atractylodis macrocephalae,Cicadae Periostracum,Bombyx Batryticatus.C4:Radix Scutellarice,almond,Thunberg Fritillary,mulberry leaf,seed of Radish,burdock seed,Fructus trichosanthes seed,Ligusticum chuanxiong,FLos magnoliae liliflorae.5.From the two herbs correlation degree,Radix glehniae and Adenophora tetraphylla,Oroxylum indicum and Radix Scutellariae,Adenophora tetraphylla and Root-bark of Chinese wolfberry,Cicadae Periostracum and Bombyx Batryticatus,Rhizoma Atractylodis macrocephalae and windproof,Tangerine Peel and Rhizoma Atractylodis macrocephalae,windproof and poria cocos,Rhizoma Atractylodis macrocephalae and poria cocos,Radix glehniae and poria cocos,Adenophora tetraphylla and poria cocos,Tangerine Peel and poria cocos,Radix glehniae and Atractylodis macrocephalae,Zhi Ke and poria cocos,Root-bark of Chinese wolfberry and poria cocos relevance is stronger,From the point of view of the correlation degree of three drugs,the traditional Chinese medicines for supplementing lung and Qi and nourishing Yin include stir-fried atractylodes sinensis,parsnips,Rhizopus japonica and Radix Nansha,and the traditional Chinese medicines for desensitizing wind include silkworm rigidity and cicada slush.Combining poria with invigorating spleen and calming the mind,it reflects that Professor Xuan Guiqi mainly uses the therapy of nourishing Yin and clearing lung,tonifying lung and invigorating qi to treat children with recurrent respiratory tract infection in non-acute infection period,and often uses the products of clearing heat and promoting pharyngeal dispersing and desensitizing.6.The analysis of disease curative effect showed that 5 patients were significantly effective,68 patients were effective,and 29 patients were ineffective.The total effective rate was 71.60%.The curative effect analysis of TCM symptoms showed that the curative effect difference was statistically significant between the TCM symptoms before treatment and the 12th week after treatment(P<0.05).Therefore,it can be seen that "Xuan’s Paediatrics" has obvious curative effect on children with recurrent respiratory tract infection in non-acute infection period.Conclusions:1.In the process of case collection and statistics,it was found that there was a close relationship between allergic history and repeated respiratory tract infection in children.2.Lung Qi deficiency is the more common syndrome type of recurrent respiratory tract infection in children,followed by lung spleen Yin deficiency.3.The treatment of "Xuan’s Pediatrics" for children with repeated respiratory tract infection mainly focuses on nourishing Yin and clearing lung and tonifying lung and qi.4.The curative effect of "Xuan’s Paediatrics"on the symptoms of recurrent respiratory tract infection in children in the non-acute infection period has statistical significance.