Objective:Based on the data mining technology,our goal is to discuss the m edication rule and diagnosis and treatment of recurrent urinary tract inf ection in nephrology department,hoping to provide relevant reference f or the clinical treatment of recurrent urinary tract infections.Methods:A total of 366 clinical cases who met the diagnosis of recurrent ur inary tract infection were collected from the nephrology department of t he First Affiliated Hospital of Heilongjiang University of Chinese Medi cine from January 1,2022 to December 31,2022.The general informatio n and drugs on the prescription of patients were sorted out and extract ed,and the prescriptions whose names of traditional Chinese medicine were well standardized were accurately recorded into the traditional Chi nese medicine inheritance computing platform(V3.0).And the correspond ing functions were selected and the traditional Chinese medicine prescri ptions were analyzed,so as to summarize the medication rules and acad emic thoughts in the department of nephrology.Results:1.This research included a total of 366 patients with recurrent urinary tract infection who had received successful treatment.There were 324(89%)female cases and 42(11%)male cases.Among them,95 patients(26%)were aged 61 to 70.2.A total of 308 traditional Chinese medicines were involved in this study,and the Chinese medicines used more than 100 times were successively:White Atractylodes Rhizome(206),Milkvetch Root(205),Poria(194),Hedyotis diffusa(191),Plantain herb(188),Chinese Thorowax Root(167),Liquorice Root(165),Lalang Grass Rhizome(134),Common Knotgrass(115),Shearer’s Pyrrosia Leaf(114),Common Yam Rhizome(114),TangShen(114),Baked Licorice(104),Lilac Pink Herb(100).3.This study included 19 different categories of Chinese herbal rem edies.Of these,the following efficacy categories were used above 100 ti mes:tonifying(1689),damp-draining diuretic(1162),heat-clearing medicina 1(883),astringent medicinal(194),wind-damp-dispelling medicinal(188),i nterior-warming medicinal(183),phlegm-resolving and cough-relieving medicinal(154),digestant medicinal(141),and damp-resolving medicinal(102).4.The analysis of the properties and flavors of Chinese herbal medi cines in this study revealed that the medicinal flavor were primarily sw eetness(3733),bitterness(3017),and pungency(1841),medicinal property were primarily cold(2541),warm(1770),neutral character(1667),and the majority of the drugs’ meridian were distributed to the lung meridian(2925),spleen meridian(2806),liver meridian(2562),kidney meridian(2410),stomach meridian(2023),and heart meridian(1665),etc.5.In this research,the dosing pattern and rule analysis produced a total of 36 core drug combinations,including 31 combinations of two d rugs and 5 combinations of three drugs,when the support level was set at 20%and the confidence level was 0.7.Additionally,a number of a ssociation rules duplicated the White Atractylodes Rhizome-Poria drug p air.6.Five groups of drug core combinations were identified as a conse quence of the cluster analysis of the study’s drug samples:Group One i ncludes the following species:White Atractylodes Rhizome,Milk vetch R oot,Liquorice Root,Poria,Plantain herb,Common Yam Rhizome;Grou p Two includes the following species:Liquorice Root,Chinese Thorowa x Root,Milkvetch Root,Poria,Plantain herb,Hedyotis diffusa;Group Three includes the following species:Hedyotis diffusa,White Atractylod es Rhizome,Plantain herb,Milkvetch Root,Common Knotgrass,Lilac P ink Herb;Group Four includes the following species:Coix Seed,Hedyo tis diffusa,White Atractylodes Rhizome,Plantain herb,Lalang Grass Rh izome,Officinal Magnolia Bark;Group Four includes the following speci es:White Atractylodes Rhizome,Poria,Milkvetch Root,Chinese Angelic a,Hedyotis diffusa,Chinese Thorowax Root.Conclusion:1.Our nephrologists think that a lack of the spleen and kidneys,w hich manifests as dampness and heat,is the pathophysiology of recurren t urinary tract infections.The fundamental tenets of the treatment shoul d be balancing the spleen and kidneys,eliminating dampness and heat f rom the sickness,reviving the blood,removing blood stasis.2.In terms of drug administration,the main drugs in drug efficacy were tonifying deficiency,clearing heat and damp-draining diuretic.The four natures of drugs are mainly cold,warm and flat drugs.The five flavors of medicine are mainly sweetness,bitterness and pungency.The main channels of drugs are lung,spleen,liver and kidney. |