| Prof. Ma Jun was engaged in traditional Chinese medicine for nearly 60 years, served as director of four generations of national Traditional Chinese medicine experts, the first famous old Chinese Medicine in Anhui Province, doctoral tutor of traditional Chinese Medicine of Nanjing University of Chinese Medicine. He committed to the study of TCM theory and its inheritance and innovation for a long term, with rigorous scholarship, and good learning experience. Especially experienced in stomach disease treatment, especially for fullness, stomachache, diarrhea, acid regurgitation, he has formed a complete set of academic theory and diagnosis and treatment system. Meticulous about syndrome differentiation and classical prescription, he has treated countless people. He pointed out that the treatment of the spleen and stomach disease is to be in the purpose of "reconciling to harmony", followed the principle of "weighing pathogenesis, lifting and dropping, dryness and moist, filling and passing, cold and heat." " Temperature, clear, eliminate, fill, reconcile, scatter, moist, rise, fall, dredge " is the ten methods of treatment of the spleen and stomach disease.The Ist part of this article introduced the academic thoughts and clinical experience of Prof. Ma. The 2nd part summarized clinical experience of treatment of spleen and stomach disease under the theory of reconciling to harmony of Prof. Ma. In the 3rd part, clinical researched on hospital preparation Shi San Wei He Zhong pills in the treatment of functional dyspepsia with liver-stomach disharmony syndrome.Part 1 Prof. Ma Jun’s academic thoughts and clinical experience1. In scholarship, Prof. Ma has well read and studied classics, followed good masters. He is Flexible in analysis and well versed in, diligent in clinic and brave in practice. He has taught and learned from others for inheritance and spread. With firmly and widely study will and constantly he has strived for perfection.2. In academic, Prof. Ma followed the overall concept of traditional Chinese medicine syndrome differentiation and the principle of respect for stomach theory, emphasizing the spleen and stomach organs doctrine in the leading position. Spleen and stomach should be the basic when reconciling yin and yang or strengthen the five internal organs.Treatment of miscellaneous disease often legislated from the stomach.Prof. Ma. He has put great emphasis on stomach, and acquired the importance that the stomach is the source of qi and blood; when spleen and stomach are strong, all organs are strong; when stomach is healthy and vigorous with adequate strength, the physical health is disease-free.3. Prof. Ma attaches great importance to "syndrome differentiation, cold and heat, asthenia and full, qi and blood" in clinical. When the diagnosis and treatment of stomach "identified evidence" is the key link, "cold and heat, asthenia and full, qi and blood" is present. Clinically, he has emphasized on Pi Qi mastering rise and Wei Qi mastering down for health. He usually uses tonic drugs for spleen disease and smooth drugs for stomach disease. Qing Wei He Zhong Tang and Xing Wei Tang are the typical prescriptions used by this theory. He has weighed the pathogenesis overall, and prominent main contradiction and co-ordination pathogenesis under the order of harmony.4. Prof. Ma is especially good at using"reconciliation method" to cure spleen and stomach diseases, combination of classical prescription, ancient prescription, time and experienced prescription with different syndrome types and flexible cutting. Treatment of stomach disease should follow the ten-character principle of "weighing, lifting and dropping, dryness and moist, filling and dredging, cold and heat". He Eliminated symptoms for acute state and remedied root of disease for non-emergency in clinical.5. During long-term of clinical practice, Prof. Ma proposed the ten methods of treatment of the spleen and stomach disease first, which is " temperature, clear, eliminate, fill, reconcile, scatter, moist, rise, fall, dredge" method, including San Han Tong Luo method, Qing Re He Zhong method, Xiao Dao Xing Wei method, Bu Qi Jian Pi method,He Zhong Xing Wei method, Shu Gan He Wei method, Yang Yin Run Wei method, Sheng Qing Yi Wei method, Jiang Ni Tiao Wei method and Hua Yu Tong Luo method. These methods concentrate on the main points, practical to clinical practice and enjoy good repeated treatment effect.Part 2 Clinical experiences in using "reconciliation method" to treat spleen and stomach disease under the guidance of "Reconcile to harmony" theory method of Prof. Ma.1.The theory of reconciling to harmony is Ma’s first point and ultimate goal during TCM treatment, "Loss of Harmony" is the basic pathogenesis of human disease, including the imbalance of qi and blood, yin and yang. Then reconciling is not only the treatment method, but also the target. "To observe the yin and yang of the place, to get the level of harmony" and "make up their deficiency, diarrhea more than" is the method of the Chinese medicine therapies. The method adjusts the relationship between yin and yang of the human body, and corrects the state of Yin and Yang, and restores the dynamic harmony of yin and yang, to let the body of the imbalance of the pathology to be processed, in order to achieve from the imbalance to the dynamic balanced state of harmony. Balance is a standard of efficacy, only to achieve dynamic "balance", in order to get truly "harmony". Harmony is the physiological status symbol of the balance of yin and yang in human body.2. Prof. Ma expounds his thought of "harmony" from the aspects of principle-method-recipe-medicines.3. Prof. Ma pointed out:"Harmonizing" method is widely used in treatment of spleen and stomach disease to achieve the balance in Zhong Jiao and recovery the function of spleen and stomach. Method and clinical application in the treatment of spleen stomach diseases mainly include the following five aspects." weigh the illness; universal elevating; dampness simultaneously; unblocked and nutritious; cold and heat treatment. Pro Card characteristic, Prof. Ma in the treatment of gastric ruffian, epigastric pain, acid regurgitation, diarrhea and other common disease of TCM has accumulated rich experience; the horse trainer function of syndrome differentiation and treatment of peptic adverse to recognize the weakness of the spleen and stomach; liver and spleen disharmony is key to the occurrence of the disease. Prof. Ma has his unique insights in treatment of prolapse of fullness, gastralgia, acid regurgitation and diarrhea.4. The application of drug pairs in the guidance of the thought of "harmony".In the diagnosis and treatment of diseases of the spleen and stomach, Prof. Ma has chosen regular drug pairs in the guidance of the thought of "harmony". He adjusts the movement of qi by using drug pairs, or uses pungent dispersion and bitter descending drug to achieve harmony. Regular drug pairs of Prof. Ma are listed.5. Cases from the analysis of Prof. Ma, the author summed up that the tutor is skilled in dialectic, legislative accurate, flexible prescription, medicational rigorous. His prescription must be due to the pathogenesis. Only when diagnosis and treatment are based on the illness, can the treatment get good effect. The number and kinds of traditional medicine can be adjusted flexibly. The number must be due to the stock and set up prescription due to illness. Only when treating in the right way to gain the effects, just such as the raft and drums. Smell of addition and subtraction, the CD can be flexible where appropriate. The author had achieved a lot, and will be get benefit for ever.Part 3 Clinical research on hospital preparation Shi San Wei He Zhong pills in the treatment of functional dyspepsia with liver stomach disharmony syndrome.1. Objective:To evaluate the efficacy and the effect of Shi San Wei He Zhong pills on the treatment of liver stomach disharmony with functional dyspepsia and its effect on gastrointestinal motility.2. Methods:80 cases meeting the inclusion criteria in patients with functional dyspepsia would be included, according to the order of treatment. They were divided into treatment group and control group, given Shi San Wei He Zhong Pills and Domperidone Tablets respectively for 14 days that is a course of treatment, and treated 2 courses totally. Symptoms of TCM, syndrome efficacy and gastric emptying before and after the treatment of each individual were compared between the 2 groups.3. The results:Shi San Wei He Zhong Pills, oral liquid and Domperidone Tablets on functional dyspepsia liver stomach disharmony syndrome clinical total efficiency were 94.7% and 81.6%, gastric emptying total efficiency was 70.3% and 73.7%, and there was no significant difference between the two groups (P> 0.05) and no adverse reaction, but Shi San Wei He Zhong Pills to upper abdominal pain, early satiety symptoms improved better than Domperidone Tablets (P< 0.05); for mental status improvement after treatment in the two groups, there was no significant difference between the two groups (P> 0.05).4. Conclusion:Shi San Wei He Zhong PilSl is a safe and effective medicine for the treatment of liver stomach disharmony, and promotes gastric emptying and prevents recurrence. |