The new low-priming cardiopulmonary bypass setup which is brought closer to the patient is one of the latest attempts in minimizing hemodilution, blood damage, and attenuating the systemic inflammatory response for patients undergoing all fields of cardiac surgery. This setup incorporates the DeltaStream diagonal pump, oxygenator, filter and reservoir with all of the features of CPB. This study is conducted to evaluate the effects in coronary bypass surgery with new system compared with standard CPB on hemodilution, transfusion, myocardial damage and systemic inflammatory response. Safety studies have demonstrated safe use of the new system in animal experiment and clinical coronary bypass surgery without any side effects. In this study, this new setup has shown significant reduction of hemodilution, reduction of the need for homologous blood transfusion, attenuation of the systemic inflammatory response and maintenance of better clinical outcome. The present study provided the potential application of this new system in cardiac surgery.
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