The Clinical And Experimental Study Of Indocyanine Green Angiography

The Rodenstock 101 type Scanning Laser Ophthalmoscope linked with the Shoulder Company Fundus Imaging System (SCIFIS) was used to perform indocyanine green angio- graphy(ICGA) and fundus fluorescein angiography(FFA) for (1)investigating the normal choroidal blood architecture, the normal filling pattern and the parameters of the choroidal circulation time; (2)for'studying the angiographic features of ICGA and the filling process of the dye both in normal and pathologic status; (3)for elucidating (combined with the use of the histopathologic examination) the involvements of choriocapillaris in the late phase of ICGA; and(4) for evaluating the safty of the ICGA in clinical use .The results in the current study were as follows:1. From the observation of the ICGA performed in the 30 normal volunteers, we found that (1)the commonest choroidal filling pattern was the type of the cilliary artery filling, the second was the type of diffuse choroidal filling . The earliest filling of the choroid was seen mostly located in the temporal area to the macula; (2)the shape of the vortex vein in the portion of scleral entering was varied among individuals, the commonest type was the "stem- ampulla type";(3) the most of the watershed zone ran vertically through the optic disc with an average width of 2.12 ± 0.51mm;(4)some abnormal changes were found in normals which were confirmed both by the Ophthalmoscopy and the FFA.