Relationship Between Oxfordshire Community Stroke Project Clinical Classification, TCM Symptom-complex Distribution And Imageology Result In The Youth And Middle-aged Cerebral Infarction

Objective:To evaluate the correlation between Oxfordshire Community StrokeProject (OCSP) clinical classification, symptom-complex distribution and imageology resulin acute cerebral infarction. To analyze the clinical feature from semeiolog, niveau diagnosis and etiology, and so as the risk factor and prognosis, so as to offer clinical proof for prevention and cure of the youth and middle-aged cerebral infarction.Methods:122 youth and middle-aged ischemic stroke patients were selected from neurology ward of our hospital, Qianfo mountain hospital and Qilu hospital cranial CT/MRI, electrocardiogram, blood biochemistry, haemorheology and ect were determined, to evaluate the blood vessel through transcranial Doppler (TCD), DSA, MRA or CTA. To divide the patients into 4 subtypes which were lacouna infarction, complete anterior infarction, partial anterior infarction and posterior infarction based on the OCSP clinical classification, and divided the patients into 5 subtypes which were Cardioembolism(CE), large artery atherosclerosis(LAA), small-artery occlusion lacunar(SAO), stroke of other determined etiology(SDE), and stroke of other undetermined etiology(SUE) based on the TOAST clinical classification so as to approach etiological factor. At the same time, to approch symptom-complex distribution. Pearsonχ2 test was used to evaluate their association.Results:Hypertension, diabetes, smoking and drinking were the main risk factor of the youth and middle-aged cerebral infarction. OCSP subtypes were moderately related with imageology subtypes; LACI was related with basal ganglion infarction and centrun ovale infarction, TACI with anterior cortical infarction, and POCI with posterior infarction; OCSP subtypes was not well related with TOAST subtypes, but LACI was well related with SAO, also TACI, PACI and LAA; Rate of large artery disease was 61%, mainly arteria cerebri media, arteria basilaris, and arteria carotis interna; The main type of lacouna infarction was sensorimotor syndrome, pure mobility next; OCSP subtypes were related with frequency and distribution of TCM Symptom-complex.Conclussion:1.Early onset artherosclerosis was the main cause of the youth and middle-aged ischemic stroke, hypertension, diabetes, smoking and drinking were the main risk factor.2.OCSP subtypes were moderately related with imageology subtypes;3.OCSP subtypes was not well related with TOAST subtypes;4.OCSP subtypes were related with frequency and distribution of TCM Symptom-complex.