1. Relationship Between Oxfordshire Community Stroke Project Clinical Classification, Brain MRI And Pattern Of Artery Abnormalities In Acute Cerebral Infarction 2. Association Of Fibrinogen Level, Gene Polymorphisms And Cerebral Infarction

Part â… : Relationship Between Oxfordshire Community StrokeProject Clinical Classification, Brain MRI and Pattern of ArteryAbnormalities in Acute Cerebral InfarctionOBJECTIVE:To evaluate the correlation between Oxfordshire Community Stroke Project (OCSP) clinical classification, brain MRI and patterns of artery abnormalities in acute cerebral infarction. To assess the predictive value of the classification of clinical symptom, brain image and artery abnormalities on the prognosis of cerebral infarction. METHODS:116 acute ischemic stroke patients were divided into 4 subtypes based on the OCSP clinical classification. Lesion distributions were classified into cortical infarction, basal ganglion infarction, centrum ovale infarction and posterior infarction according to brain MRI image. Artery abnormalities were grouped into large artery disease and small artery disease according to the results of transcranial doppler, brain MRA, carotid duplex sonography or cerebral angiograph. Pearson x~2 test was used to evaluate the association of OCSP subtypes, brain image subtype and patterns of artery abnormalities. The neurological function of patients 1 year after onset was evaluated by Barthel index and Rankin scale. Kaplan-Meier survival curves were graphed, and log-rank testing was performed to investigate the differences among stroke subtypes. RESULTS:...