Nourish Yin And Moisturize Dryness Prescription United Chemoradiotherapy On The Treatment Of Breast Cancer Belong To Deficiency Of Yin In Clinical Research

Objective:To observe the short and long-term treatment effect of Nourish yin and Moisturize dryness Prescription united chemoradiotherapy in the breast cancer which belong to Deficiency of Yin. Through the assessments of patients in the aspects such as TCM clinical symptoms, quality of life, tumor size changes, the long-term survival indicators, obtain more about the treatment value in clinic, and exploit more wider future in TCM remedy to breast cancer.Methods:105patients with advanced breast cancer belong to deficiency of yin were devided into two groups, treatment group (nourish yin and moisturize dryness prescription united chemoradiotherapy with70cases), control group (treated with radiotherapy and chemotherapy)35cases. Four times of treatment were observed in the two groups before and after treatment, clinical symptoms, quality of life changes. At the same time, long-term efficacy such as long-term TCM symptoms, survival rate were be observed.Results:(1) TCM symptoms:treatment group TCM Syndrome cured,11cases,52cases effective, ineffective in7cases, the effective rate of90.0%; control group,3cases markedly effective21cases,11cases, the effective rate of68.6%. The statistical test, two groups have differences (P <0.05). It means nourish yin and moisturize dryness prescription united chemoradiotherapy is superior to the control group.(2) Tumor size change:the treatment group complete remission0cases, partial remission in17cases, stable48cases,5cases of disease progression, lesions and stable rate of92.9%; the control group, complete remission0cases,7cases of partial remission, stable23cases, five cases of disease progression and stable lesions was85.7%. Showed no significant difference (P>0.05).(3) Karnofsky score:After treatment, see KPS score was significantly improved compared with before treatment were significantly different (P<0.05). The control group after treatment KPS score also improved significantly (P<0.05). After treatment, statistically significant differences (P<0.05), suggesting that the Yin and moistening method with radiotherapy and chemotherapy in advanced breast cancer Yin Jin deficiency syndrome patients physical status of the improvement is more obvious.In addition, the long-term efficacy results show that70patients plus traditional Chinese medicine on the basis of radiotherapy and chemotherapy, the survival of the efficacy effective in10cases, accounting for14.3%; effective51cases, accounting for72.8%; ineffective in9cases, accounting for12.9%; The total effective rate was87.1%. The control group survival of total effective rate was74.3%. The treatment group survival in patients with3-year survival rate was67.1%;5-year survival rate was31.4%.3-year survival of the patients in the control group survival was45.7%;5-year survival rate was17.1%.Conclusion:Nourish yin and Moisturize dryness Prescription united chemoradiotherapy has good efficacy in short and long-term in advanced breast cancer belong to deficiency of yin syndrome, can significantly improve the clinical symptoms and physical condition, and can prolong the survival of patients.