The Associations Of Clinical Epidemic And Dermatologic Characteristic And CD4 Cell And HIV-VL Of HIV/AIDS Patients

ObjectivesThrough the first clinical visit of 690 cases of HIV/AIDS, find the co-relationships on epidemic and dermatologic characteristics, immunological status and HIV-VL of HIV/AIDS infection. To provide basic references for physicians on prevention and treatment of the disease.MethodsEstablish database of 690 cases HIV/AIDS positive patients, using their initial clinical/hospital diagnosed record, and to analyze using SPSS13.0.Results(1) The ratio of male and female HIV/AIDS patient is 2:1;(2) Patients age are ranging from 20 to 50, average is 35.3.(3) Sexual transmission has become the main transmission channel, including heterosexual 16.7%, homosexual 17.5% (mainly from higher educated people in Beijing), bisexual 11.6% and couples 7.8%, indicating HIV/AIDS is now transmitting from highly infected people through those"bridge people"to general public. HIV/AIDS infection through blood contamination is 30.6%, mainly from Henan, Shanxi, Anhui and Hebei provinces, through IV drug use is 2.6%, and mother to children is 2.6%. ts are: skin disease 47.3%, pneumonia 16.6%, upper respiratory tract infection(4) About 51% of the patients were found at general hospital instead of specialized hospital for contagious diseases. 10.1% are found through skin and STD (mostly syphilis, condyloma acuminatum and skin eruptions). Others are 38.9%.(5) The top five diseases on initially-diagnosed HIV/AID infected patien 14.2%, hepatitis 14.2%, digestive tract moniliasis 6.8%. Others have TB, CNS infection and PCP, few cases with Cryptococcus meningitis, toxoplasmosis, non-tuberculosis mycobacteriosis, and marniffi penicillium diseases.(6) Skin diseases found are in the order of: candidiasis of oral mucosa, herpes zoster, condyloma acuminatum, syphilis, pruritic papular eruption, oral ulcer, drug eruption, dermatitis and eczema and dry skin (xerosis). Those diseases mostly occur during AIDS period.(7) Patients usually have already developed severe immunodeficiency at initial diagnosis, with multiple diseases and opportunity infections. 37.3% of the patients'CD4 count <50 cell/ul, 32.8% <200 cell/ul, only 29.9% of the patients'CD4 count >201 cell/ul.(8) Our data indicate that the higher HIV-VL, the lower CD4 count will have more dermatoses and complications. Conclusions(1) Higher ratio of female HIV/AIDS infections may expedite the transmission of the HIV/AIDS. As sexual transmission has become the major channel, with significant heterosexual and homosexual activities, and transmitting through"bridge people"to the general public. Everyone should be aware of the situation and prevent the disease from spreading.(2) HIV/AIDS Patients are usually diagnosed at general hospital instead of specialized hospital for contagious diseases. It is important to have the antibody monitor system in place to find the HIV/AIDS infected patients at early stage. Also, strengthen the check ups on dermatology/STD, in-patients, newly weds, etc.(3) As the high tendency of skin disease diagnosed due to HIV/AIDS infections, dermatologists should be highly alerted to diagnose the diseases accurately and as early as possible.(4) This thesis is aimed at emphasizing the importance of diagnosis HIV/AIDS infections at the first place to prevent the disease from spreading.