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Vietnam Traditional Medicine To The Medical Literature Research And Treatment Diabetic Nephropathy 261 Clinical Cases Legislation Retrospective Analysis

Posted on:2010-03-04Degree:DoctorType:Dissertation
Country:ChinaCandidate:C Y ChenFull Text:PDF
GTID:1114360275966017Subject:Chinese medical science
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The Diabetic Nephropathy(DN) is a frequent chronic capillaries complications of Diabetes Mellitus(DM) and difficult to be cured,having become one of the main cause of deaths of the diabetic.The Diabetic Nephropathy is the main reason that causes eventually in last phase the kidney disease (the end-stage renal disease,ESRD) in developed countries,about 30%- 40% diabetic will develop into the diabetes kidney disease,then developed into the ESRD,and the ESRD outbreak rate is year by year rising.The modern medical treatment mainly is various disease and factor that controls the blood sugar, controls the blood pressure and rectifies the fat metabolism mess with other influence kidney function,once entering the kidney function to crock up the stage,an ability is dialysis or kidney transplantation.But the Chinese medicine cures the DN,not only improved the clinical symptoms,the protection of renal function,slow down and stop the disease progression of renal damage and improve quality of life in patients with DN,and the poisonous side effect is very small,by the international medical attention.Vietnamese traditional medicine by the influence of Chinese medicine it is.Therefore the Vietnamese tradition of medical research and treatment of diabetic nephropathy in Chinese medicine inevitably involves.Vietnamese traditional medicine as a result of special historical and geographical relations,the Vietnam Traditional Medicine and Chinese Medicine to seek effective measures to control the DN and the therapeutic drug,is a topic of concern.ObjectiveThrough literature research and analysis of modern statistical methods, and explore the evolution of diabetic nephropathy and the treatment of the laws of the track,hoping to be able to provide effective prevention and treatment of diabetic nephropathy and learn more new ideas.First of all,learn the methods of use of literature,organize the collection of ancient literature, from the perspective of historical development of ancient medicine on diabetic nephropathy about a comprehensive summary and review.Analysis of the disease evolution of diabetic nephropathy,etiology,pathogenesis,differentiation, in principle,treatment,prescriptions and many other aspects to the overall understanding of the development of diabetic nephropathy syndrome differentiation rules of literature to lay the future of basic research.Secondly,the combination of the DN observed large sample of cases, evidence of various types of symptoms,examination of the target to use scientific statistical methods for analysis.DN at the standardization of Chinese medicine clinics,the objective of providing more reliable on the basis of clinical and clinical exploration of more effective treatment methods to provide a basis to make it more comparable and scientific.MethodResearch program:A retrospective survey design research methods.Research principles:Strict accordance with the selected criteria, diagnosed in patients with diabetic nephropathy.Collection,including the general situation,personal past history,their own symptoms,laboratory tests, treatment modalities,such as statistical analysis of data.Sources and case study:In order to select a reasonable source of information,increase the credibility of clinical research,the development of our region such as Vietnam,where the research unit for the hospital;to patients with diabetic nephropathy were studied;to determine the use of Vietnamese traditional medicine for the treatment of Chinese traditional medicine Retrospective clinical investigation and research information.Record Content and Methods:The researchers need to fill in for cases "in patients with diabetic nephropathy questionnaire retrospective study",Record of Vietnamese traditional medicine used in treatment programs(including the completion of treatment),as well as treatment.Clinical researchers take part in the training must go through a full understanding of clinical research programs and the inspection target.In completing the form,fill in error shall not be altered if there can be designated line and go right up next to the content of written and signed amendment to amend the date and name.Statistical Analysis Methods:①Test standards:All statistical tests are used both tests,P values less than or equal to 0.05 by the test will be considered statistically significant difference,if the test meaningful differences,the two make the comparison.②Statistics Description:Variable will use the average value±standard deviation for descriptive statistics; classification using variable frequency(rate) for statistical description.③Analysis:Multiple analysis of variance with measurement data,compare the two using the t test;sample rateχ~2 test data using Level rank sum test.Results1.General information on the study:In this study,261 cases of diabetic nephropathy,the source of three years,do the Vietnamese hospital in-patients, are consistent with the clinical diagnostic criteria for DN.Man one of 121 cases,140 cases of female;the ratio of male and female patients 1:1.16;the youngest was 34 years old,maximum 76 years old,the average age of male patients than female patients(59.45±7.41,56.11±7.79),with an average age of 57.66 years old±7.78.12 cases of early,224 cases of clinical stage, 25 cases of late;Treatment:63 cases markedly effective(24.1%),115 cases of effective(44.1%),83 cases of invalid(31.8%),there is statistical significance(P<0.01).2.Evidence-based analysis2.1 Deficiency organs according to five criteria for research:Five organs of diabetic nephropathy Kidney Deficiency in evidence(47.5%) were much, followed by spleen deficiency(35.6%),lung deficiency(3%) and liver deficiency(5%) is less common,there is statistical Significance of study (P<0.01).PhaseⅡDiabetic Nephropathy Kidney permit the highest incidence (41.6%),but no statistical significance(P>0.05);ⅢPhase,Ⅳcertification period the incidence of kidney deficiency are the highest(48.6 percent each, 51.3%),Ⅴa view to spleen deficiency with the highest incidence(52%),there is statistical significance(P<0.01).2.2 According to yin and yang,qi and blood deficiency Standards: Deficiency of yin and yang qi and blood of diabetic nephropathy in Yin-deficiency(46%) as much,followed by Qi(27.2%),blood deficiency Standards(18.4%) and Yang(8.4%) were less common,there is statistical Significance of study(P<0.001).PhaseⅡDiabetic Nephropathy deficiency permits the highest incidence(41.7%),PhaseⅤ:Qi highest incidence(32%), but no statistical significance(P>0.05);ⅢPhase,ⅣPhase permit the incidence of deficiency are the highest(56.7%,46.5%),there is statistical significance(P<0.001).2.3 According to a variety of complex research evidence standard:Diabetic nephropathy with compound deficiency of Qi-Yin Deficiency card(41%) as much, followed by spleen and kidney Qi deficiency(31.4%),deficiency of yin and yang of two(4.2%) kidney and lung deficiency(3.4%) than rare,and there is statistical significance(P<0.001).PhaseⅡdiabetic nephropathy,ⅢPhase,Ⅳcertification period the incidence of both Qi and Yin deficiency are the highest(58.3 percent each,32.4%,43.8%),and were statistically significant (P<0.001);Ⅴperiod Spleen and Kidney Qi deficiency in the highest incidence (32%),but no statistical significance(P>0.05).2.4 According to the standard empirical research:Evidence of diabetic nephropathy with blood stasis syndrome(39.8%) were much,followed by wet and humid certification card(all for 17.2%,16.5%),gas stagnation(7.2%) were less common,there is statistical significance(P<0.05).PhaseⅡdiabetic nephropathy,ⅢPhase,Ⅳphase,Ⅴphase evidence of the incidence of blood stasis are the highest(58.3 percent each,43.2%,38.5%,36%),and were statistically significant(P<0.05).3.The evidence-based laboratory investigations before and after treatment comparison of measured values:The type in the target blood glucose levels after treatment were significantly lower before treatment,there was a significant difference(P<0.01).Various types of renal function after treatment than before treatment target a marked improvement,with significant difference(P<0.01 or P<0.05).After treatment at various types of CHOL,TG, HDL-C,LDL-C to improve significantly,compared with before treatment,with significant difference(P<0.01).After treatment at various types of ApoA, ApoB improve significantly,compared with before treatment,with significant difference(P<0.01 or P<0.05);various types of blood pressure after treatment were significantly decreased,compared with before treatment,there is significant difference(P<0.01).ConclusionDiabetic nephropathy is the international medical research at this stage the most popular.The impact of larger,high mortality,is in urgent need of solution in today's major illnesses.Modern medicine has not yet ideal and methods of treatment.We all hope that the treatment with traditional medicine. This article from the perspective of the Vietnamese traditional medicine, through research and documentation of the Vietnamese traditional medicine clinical diabetic nephropathy in a retrospective analysis of case study to examine the treatment of the Vietnamese traditional medicine prescriptions DN of the certificate and its associated governance principles and we hope for the clinical and DN scientific research to provide some new ideas and methods.The purpose of this study include the following:1.The use of literature methods to collect,summarize,collate information on ancient and modern literature,the system of diabetic nephropathy(DN)-related disease,pathogenesis,treatment,medication.v.v. As a result of the Vietnamese traditional medicine and the close relationship between Chinese medicine and the history of mutual exchanges between the two countries,through the ancient and modern.The same theoretical system. Therefore,this article on Vietnamese traditional medicine in the diagnosis and treatment of diabetic nephropathy is bound to deal with a long history of Chinese medicine.We found that the Vietnamese and Chinese traditional medicine in diabetic nephropathy and the clinical research there are many common features.Vietnam and China but also has characteristics with irreplaceability.Vietnamese traditional medicine in particular,has obvious geographical characteristics,and Chinese medicine has a strong complementary advantages;the treatment of diabetic nephropathy both experience and research results can be rapid and effective communication.Both produced a large number of authentic ingredients can also be used through the border trade.Studies have shown that the Vietnamese traditional medicine used in the treatment of diabetic nephropathy with Chinese brand of a large number of "Northern medicine" on a good reflection of this.2.In this paper,the use of statistical methods,traditional medicine of Vietnam 261 cases of clinical diabetic nephropathy cases were retrospectively analyzed the findings of a study of patients with DN in the performance of Kidney evidence-based(47.5%),followed by spleen deficiency (35.6%).Kidney Deficiency DN stages throughout;Ⅴphase with the highest incidence of Spleen Deficiency Syndrome(52%),spleen and kidney may lead to false DN an important factor in the progression of the disease.Poor kidney function always affects the course of the development of DN,spleen function of poor course of the development process and is closely related to DN.This is a critical period of diabetic nephropathy where the role of important tips. The study found that patients with DN to Qi Yin deficiency(41%) for many, followed by spleen and kidney Qi deficiency(31.4%),blood stasis syndrome (39.8%).PhaseⅡdiabetic nephropathy,ⅢPhase,Ⅳphase,Ⅴphase evidence of the incidence of blood stasis were higher(58.3 percent each,43.2%,38.5%, 36%),blood stasis can be seen throughout the course of DN,With the health of poor,wet card,damp-heat syndrome;wetlands permit a gradual increase in turbidity,water gradually increase metabolism disorders.These stages of diabetic nephropathy treatment has an important reference value.3.In this study,through literature and clinical analysis of a retrospective study of cases of Vietnamese traditional medicine diagnosis and treatment of diabetic nephropathy Treatment prescriptions a certain understanding of the law.Found a lot of Vietnamese traditional medicine is more effective treatment of diabetic nephropathy in the methods and prescriptions.In particular,a number of geographical features of Vietnam's "Southern medicine",diabetic nephropathy on clinical applications and research have greater value and potential.This article also describes a professor of clinical syndrome differentiation of diabetic nephropathy identified a number of well-established unique experience and methods.This is to discuss the Diagnosis and Treatment of diabetic nephropathy have a good reference.
Keywords/Search Tags:Diabetic Nephropathy, Differentiation Treatment, Clinical Research, symptom research, Syndrome research, Investigation
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