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Study On TCM Syndromes Of Metabolic Syndrome

Posted on:2014-02-02Degree:DoctorType:Dissertation
Country:ChinaCandidate:L JinFull Text:PDF
GTID:1224330401455588Subject:Chinese medical science
Abstract/Summary:PDF Full Text Request
Objective:To investigate the relationship between TCM and MS group, provide objective basis for clinical detection of possible to determine various syndromes, through clinical epidemiological investigation of multi-center, large sample, study and explore the adult MS TCM Syndrome Types and distribution system in China, the establishment of the main symptoms, provides the reference for the Chinese intervention in the future to better guide the metabolic syndrome.Methods:By the study group interviews and a questionnaire survey made by experts "metabolic syndrome clinical questionnaire", Beijing Yangfangdian Hospital, Nanjing built in the hospital of traditional Chinese medicine, Shandong traditional Chinese Medicine Hospital of Jining City, Shandong Rizhao Huafang hospital, Shanxi Chinese medicine hospital in Changzhi City, Shanxi Luan Mining Group Hospital, Liaoning Benxi Chinese medicine hospital, Hebei Province, Baoding First Hospital of traditional Chinese medicine8centers, cross-sectional survey. A cross-sectional survey in2005, the International Diabetes Federation (IDF) on the metabolic syndrome was defined as the diagnostic criteria of TCM syndrome, by1997of the people’s Republic of the national standard "TCM clinical terminology syndrome part"(GBVT16751.2-1997) diagnostic criteria. A choice of8centers in Beijing, Nanjing, Benxi, Luan, Changzhi, Jining, Rizhao, Baoding, included1842cases of patients with metabolic syndrome as the observation group, at the same time into312healthy samples as normal control group, collect the general information and the information of four diagnostic methods, and the human body measurement, medical history, diet, exercise, living habits and related clinical lab index detection etc.. Establish a network database, these data double double entry database, statistical analysis was performed using SPSS19.0statistical software. Using frequency statistics analysis (frequency analysis) method of TCM four diagnostic information, including the calculation of the positive rate of the clinical symptoms, signs and tongue pulse index, and the case group and control group. Chi-square test analysis (Chi-square analysis), combined with the clinical diagnosis and expert opinion, preliminary screening index. Using exploratory factor analysis (EFA) method for further research on the four diagnostic information, extract the common factor, and the theory of traditional Chinese medicine will be common factor with syndrome name specification name, establishment of metabolic syndrome common syndrome. After calculating the factor scores, the highest value to determine the metabolic syndrome syndrome distribution. At the same time, to investigate the relationship between TCM and MS group MS every card points.Results:Based on the statistical results of factor analysis and cluster analysis, expert opinion, determine the initial syndrome name of metabolic syndrome and the distribution rules of syndrome of liver and kidney yin deficiency (17.9%), hyperactivity (22.3%), phlegm stasis syndrome (28.4%), spleen dampness syndrome (17.7%), stagnation of phlegm-dampness syndrome (7.8%), accompanied with blood stasis syndrome (5.9%)To explore the relationship between6syndrome and MS syndrome main group of MS, the results are as follows:①High BMI and high WHR may microcosmic syndrome differentiation based on blood stasis as MS and folders. At the same time, but also as judge the deficiency and empirical reference.②SBP can be as reference judge MS anger hyperactivity card, phlegm each node card, for deficiency identification, and DBP can be used as MS and folders microcosmic syndrome of blood stasis basis, but also as a judgment MS anger hyperactivity card, phlegm each node card reference.③FPG Overabundant Liver-Fire, phlegm stagnation syndrome, phlegm each end to permit the highest. Anger hyperactivity syndrome and liver kidney yin and folders blood stasis was statistically significant (P<0.01). More than in the hot the Yin stage of MS patients with FPG relative maximum. Accordingly, the clinical syndrome reference.④TC aspects, liver and kidney, the lowest card, and each node card with the top three phlegm, Overabundant Liver-Fire Spleen wet Sheng card statistically significant. TG, liver and kidney highest certificate, phlegm each knot card, Overabundant Liver-Fire Spleen wet Sheng card lower. HDL-C, phlegm each node card minimum, with other syndromes groups were significantly different (P<0.01), can be used as MS phlegm each knot card micro-dialectical basis.Conclusion:Distribution of TCM Syndromes of metabolic syndrome, phlegm heat, deficiency, that blood stasis is the key point of the differentiation. Combined with statistical method the results obtained with the metabolic syndrome clinical onset regularity basically by syndrome differentiation of traditional Chinese medicine, the "metabolic syndrome common syndrome study" for this disease further standardization research and provide methodology reference, and also provide reference and basis for the clinical diagnosis and differentiation of the disease treatment the implementation of.
Keywords/Search Tags:metabolic syndrome, TCM syndrome, cross-sectional survey, factoranalysis, cluster analysis
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