Study On Self-assembly And Photophysical Properties Of Pyrrole Derivatives

Pyrrole is a kind of very important chemical compound, most of whose derivatives extensively exist in nature, such as hemoglobin, vitamin B12 and bilirubin. Pyrrole derivatives in the physiology and life of animal and plant play very important roles. Other compounds, for example, pyrrole Schiff base, porphyrin photosensitizers and sodium copper chlorophyll in, are also pyrrole derivatives. In this paper the assembly of pyrrole derivatives, the physical properities of two kind of photosensitizer porphyrins and anti-freeradical property and application of sodium copper chlorophyllin are investigated.J M Lehn, a Noble Prizer, bought forward the concept of supramolecular in 1987,which study on thechemistry of supramolecular or formation, character and application of molecular suprastructure. The formation of supramolecular implement by molecular assembly, the concept of which is that in a certain condition ligand molecular and host molecular build up a special construction supramolecular. It is very important to construct complicated molecular, biological molecular especially. The use of metal ions and ligands in supramolecular assemblies has been extensively studied in recent years. Among many ligands designed by chemists, the polybipyridine ligands developed by Lehn and his colleagues are particularly interesting. Due to the nature of the ligands (neutral), these complexes are charged species. Therefore, counterions must be used to generate neutral compounds. This may result in competitive binding between the counterion and the ligand, which is usually overcome by the use of specific noncoordinating counterions. Unfortunately, this type of counterion often gives rise to considerable disorder in the solid state. In contrast to pyridine, pyrroles were recently found to be ideal building blocks for supramolecular assemblies. In pyrroles, the hydrogen at the N-H group can be removed and the resulting mono-anionic species is a resonance stabilized ligand. The complexes generated by pyrroles and metal ions are neutral species. Therefore, counterions are not needed. Consequently, it is particularly convenient to purify the complexes by column chromatography since they are not charged and are generally the least polar component in the reaction mixtures. In the second chapter a tetrapyrrole nickel complex, three pyrrole Schiff base nickel complex and a silver pyrrole complex are synthesized and crystals of them are obtained. We use X-ray method to determine and analyze the structure of these crystals. The Fourier-transform Raman (FT-Raman) and infrared (FT-IR) absorption spectra of the tetrapyrrole nickel complex have been investigated. This paperreports the first silver network polymer formed through the self-assembly of bis (pyrrol-2-yl- methyleneamine) with silver nitrate, in which the silver centers are bonded to the C-N bonds of pyrrole ring in r|2 fashion. This provides a new approach to design and synthesis new ligands and use these ligands to form Ag( I)- it supramolecular self-assembly.The aim of photodynamic therapy is to eliminate the focus tissue in human body and not damage the normal tissue. In photodynamic therapy process photophysical process is very important, excited photosensitizer reach the triplet state by intersystem crossing, which is spin-banning process. So the lifetime of triple state is longer and photosensitizer in triplet state has chance to exchange the energy with neighour molecular (type II) or electron transfer (type I). Because photosensitizing effect must do through triplet state of photosensitizer, it is very important to investigate its photophysical properties physical propertise the triple state especially. In the third chapter photophysical properities of two kinds of chlorin photosensitizer is investigated. The results show that both of them have higher triple state quantum yield and longer fluorescence lifetime and triple state lifetime. The result of these investigation and study on the properties of photochemistry and photobiology prove that two photosensitizer are high quality ones.T...