The Study Of BAWEIQiangHuo Dispersible Tablet On Common Cold

The dispersible tablet have effect of clearing away heat and antitoxin, anti-inflammation and diminishing pain. It is used as curing for common cold. It has remarkable curative effect and small harmful reaction through long clinical practice. However, It has some disadvatages, such as taking large dosages every day, harmful toextractableand inconvenient to eat and so on. So I studied the dispersible tablet.We adoptβ-CD hpypersound method to include volatile oil. The optimized inclusion technology conditions followed as: volatile oil dissolved in 2times alcohol, the proporation between volatile andp-CD is one to four,hpypersound 45min, 6times water.The best conditions for Ammi majus extraction technology as followed: degradation the medical material to coarse powder, use 6times 70% alcohol as solvent, immerse 2 hours, percolate speed is 1 ml·kg^-1·min^-1.The optimized extraction technology followed as: the five kind of herbs were crashed to coarse powder, add alcohol to distilled water solution and made it became 50% alcohol solution as percolate liquor, percolate speed was 1 ml·kg^-1·min^-1. The optimized extraction technology of rehmannia followed as: immersed 4 hours, extracted two times with 10times and 8times water for 1 hour each. The best extraction technology of baical skullcap root followed as: extracted with water for 3 times(8times, 6times, 6times), every time 2 hours.The optimized refinement technology of baical skullcap root followed as: adjust extract to pH 1 to 2 with acid hydroc. The deposition (baicalin) dissolved with 40% NaOH solution The solution adjust pH to 7 and add equal amount of alcohol then use acid hydroc adjust pH to 1 to 2. Heat the solution to 80℃. When baicalin deposited we used 50% alcohol washing 6times.Optimum preparaion process:add inside bulking agent MCC (20%) and percentage constancy(L-HPC: MCC:CCMS-Na =1:9:3)12% disintegrant, to use 4%SLS70% alcohol granulate, out inside percentage constancy(L-HPC: MCC:CCMS-Na =1:9:3)8% disintegrant,add clathrate, tabletting, to obtain.Adopt TLC to distinguish four herbs, examine each index on the basis of the rule of...