Preparation And Electrochemical Sensor Application Of Ferrocene And Its Derivatives Modified Electrode

Due to the unique character of ferrocene and its derivatives such as optical, electrical and catalytic character, ferrocene derivatives have attracted much attention of many chemists for their application in modified electrode. In this paper, ferrocene derivatives modified electrode has been fabricated by combining some novel technique with electrochemical method. Besides, ferrocene derivatives modified electrode fabricated by us has been taken into the study on electrochemical biosensor.First, ferrocene carboxylic acid (FCA) was immobilized in the cavity ofβ-cyclodextrin (β-CD) polymer by host-guest reaction, meanwhile fresh albumen, which is a kind of convenient, facile and cheap material, was used as cross-linking agent replacing of glutaraldehyde. Both the forming ofβ-CD/FCA inclusion complex and the participant of cross-linking agent greatly improved the stability of the modified electrode. The modified electrode showed a good electrochemically catalytic activity for the oxidation of ascorbic acid and also can eliminate the interference of dopamine.Secondly, based on the fact that cyclodextrins can be adsorbed at the surface of carbon nanotubes by van der Waals force and hydrophobic effect,β-CD firstly formed inclusion complex with ferrocene (Fc) and then single-walled carbon nanotube (SWNT) was dispersed in the inclusion complex with the aid of ultrasonic. So Fc/β-CD/SWNT modified carbon electrode was fabricated by coating. Then the properties of this electrode and its electrocatalytic oxidation of uric acid (UA) were investigated in detail. The results have shown that UA can be electrocatalyzed at the...