Study On Preparation Process And Elementary Stability Of Radix Astragali Injection

Background:Radix Astragali Injection with effects of immunomodulation, anti-hypertension, anti- inflammation, and blood circulation promotion, is used to treat viral myocarditis, viral hepatitis and cardia insufficiency. According to the drug standard of Chinese traditional patent formulation promulgated by the Department of Health of People's Republic of China (WS₃-B-3335-98), there are two kinds of small volume parenteral (SVP) solution of Radix Astragali Injection on sale: one is 2mL per-ampoule corresponding to 4g native herb, the other is 10mL per-ampoule corresponding to 20g native herb. The administration route can be intramuscular injection or intervenous drop infusion.At present, Radix Astragali Injection is often used by intervenous drop infusion in clinical therapy. Because we could only get the small volume dosage form of Radix Astragali Injection, so we'd have to add it into other large volume parenteral(LVP) solution to get the large volume Radix Astragali injection for intervenous drop infusion. The process is complicated and the injection is easy of being polluted. In clinical using, staff usually adds Radix Astragali injection into LVP straightly, that is a inconvenient operation process which could increase the possibility of foreign...