Study On Preparation And Quality Standards In Qintment Qufeng Liangxue

Qufeng Liangxue liposome cream is composed of eight Chinese medicinal herbs,which is an effective prescription to cure Qufeng Liangxue.It has the functions of Qufeng dampness,promoting the emergency of liver and kidney and activating blood circulation and dissipating blood stasis.The main topics of medicinal raw materials extraction process,liposomes ointment forming process,quality standards and the stability of formulations were studied.Most of the active substances in the prescription and theri pharmacologic action have been identified on the whole.Based on the former study results,the experiment extracted active substances according to their physical and chemical properties.Soaking time was studied singly.The potential influence factors to the performance of extraction were fully considered.The techniques of alcohol extract was designed in scientific and reasonable way with orthogonal design.The reasonable extract equipments and technique conditions were optimized by taking those representative effective constituents as citerion.Also,the process conditions of and formulation were studied before the processing parameters were determined.In order to guarantee the quality and curative effects of Qufeng Liangxue liposome cream, quality standard its set up was with the help of modern science and technology,such as TLC and HPLC. After a series of experimental studies,the most important traditional Chinese medicine herb in the prescription was controled quantitatively,and the quality standards were established.In addition,primary stability was tested in three lots of pilot study samples during the period of six months,and all the items covered the certification.The experimental result suggested that the technology of Qufeng Liangxue liposome cream convenient and feasible,the physical and chemical properties stable and the quality controllable.