Study On The Key Technology Of Clinical Evaluation Of Qi Deficiency And Blood Stasis Syndrome Based On Literature Research And Epidemiological Investigation

To explore the essential factors of clinical evaluation in treating qi deficiency blood stasis syndrome (QDBSS). To find out the reasonable way and scientific method of diagnosis and effect appraisal of QDBSS through literature retrieval and epidemiological investigation.Literature researchObjective:To find the disease which are diagnosed with QDBSS and to study the essential factors of diagnostic criteria, effect appraisal, and duration.Methods:A search strategy was designed to select published literature focusing on QDBSS from Chinese National Knowledge Infrastructure (CNKI) database and wanfang database according to certain. The frequency of key information in these search strategy were calculated, summarized and analyzed by SPSS 19.0.Results:892 papers are included in the research, in which the disease that diagnosed with QDBSS including stroke, coronary heart disease and heart failure and so on. Only two papers mention QDBSS duration, respectively are one month and two month. In addition, the average period of treatment is 1.32 month, refer to disease diagnosed with QDBSS. Diagnostic criteria mainly consist of Drugs Clinical Research Guiding Principle-2002, Criteria for the Evaluation of Curative Effect for Stroke-Encephalopathy emergency of State Administration of Traditional Chinese Medicine, Diagnosis of Disease and Curative Effect of Traditional Chinese Medicine Standard Line-1994, Combine Traditional Chinese and Western Medicine Research Institute in 1986 Formulated the Standard of Deficiency Syndrome of Traditional Chinese Medicine, Diagnostic Criteria of Blood Stasis Syndrome and Internal Medicine of Traditional Chinese Medicine.319 of 892 papers state symptoms and signs of diagnosis to QDBSS, which the top ten most frequent are fatigue, short of breath, tongue lilac, tongue with the blockage points, palpitation, weak, spontaneous perspiration, pale complexion, chest pain, white coating on the tongue.121 papers indicate the source and reference of QDBSS curative effect valuation standard.Epidemiologic Research:Objective:A physician recognition questionnaire was produced to find out the key techniques of clinical assessment for QDBSS, based on the result of literature research. The essential factors of clinical evaluation cover representatives disease, diagnosis standard, signs and symptoms, treatment and curative effect evaluation index/standard elements, etc.Methods:Physicians in Guang’anmen Hospital, Xiyuan Hospital, and Beijing traditional Chinese medicine hospital were selected to be investigated. Related apartments physicians mentioned in the literature research results were incorporated into the questionnaire investigation.Results:The physicians were investigated in these three hospitals from Januaryto March 2015. A total of 440 questionnaires were conducted to face-to-face interviews, and 439 questionnaires were returned (response rate 99.77%). Main representative diseases of QDBSS were coronary heart disease, stroke, lung cancer, and diabetic nephropathy etc. The characteristic signs and symptoms of QDBSS include tingling, fatigue, tongue with teeth marks, etc. The focus of symptoms were switched from qi deficiency syndrome to blood stasis syndrome, with the improvement of physician level. Average duration of QDBSS is 2.82 month. The multiple symptoms improved with four classification method (42.79%) and all symptoms of the whole syndrome improved with four classification method (24.59%) were mainly selected as a curative effect valuation.Conclude:Respectively using the method of literature research and epidemiological investigation, to describe the frequency distribution of QDBSS period of treatment, representative disease, and clinical evaluation, which from clinical literature reports and the questionnaire survey. Combination with disease, symptomand syndromeisthe precondition of curative effect evaluation of QDBSS, and the treatment course is the key to the clinical evaluation process of QDBBS. Meanwhile, symptom index make up the fundamental elements of curative effect evaluation. The preliminary results reveal the evaluation factors of the key technology of QDBSS, to provide a new idea for the clinical syndrome efficacy evaluation of traditional Chinese medicine.