The Effect Of Copper Glycine On Growth Performance And Related Biochemical Index Of Weanling Piglets

To study the effect of copper glycine and copper sulfate(250 mg·kg-1) on growth performance, immunity, blood biochemical and hormone indexes of weanling piglets ,the experiment were designed..96 weanling piglets (8.36±0.14㎏)were randomly distributed into four groups with four replications, six of each. Piglets in control group were fed basal diet which added 250 mg·kg-1 copper sulfate, while the diet of experimental groupsⅠ,ⅠandⅠ, they were mixed 250 mg·kg-1, 125 mg·kg-1 and 62.5 mg·kg-1 copper glycine, respectively. The experiment lasted for 30 days.The results showed that:Compared with the control group, FBW of experimental groups had no significant difference, while ADFI and F/G of groupⅠdecreased by 21.3%(P<0.05) and 11.9%(P<0.05), respectively.The digestibility of CP, EE and CF had no significant difference among the groups.The blood physiologic index (RBC, WBC, HGB) also had no conspicuous change.Compared with the control group, the level of BUN in groups ofⅠandⅠdecreased by 14.25%, 7.26%, respectively, while groupⅠincreased by 17.47% (P>0.05) The GLU content in groupⅠ,ⅠandⅠincreased by 7.53%, 1.76% and 4.81% (P>0.05), respectively.Compared with the control group , IgG content in GroupsⅠandⅠincreased by 9.8%, 11.76%, respectively (P>0.05), and IgA level in GroupⅠ,ⅠandⅠincreased by 4.76%, 23.81% and 19.05%, respectively (P>0.05). IgM in GroupⅠandⅠincreased by 40.91% and 13.64% , respectively(P>0.05), while C3 levels had no remarkable difference (P>0.05).Compared with the control group, the amount of CP in GroupⅠa ndⅠhad decreased by 16.75%, 21.25% (P<0.05), respectively, but that in the group ofⅠincreased by 17.44% (P>0.05). Levels of GSH-PX in GroupⅠ,ⅠandⅠhad decreased by 2.1%, 7.42%, 8.83% (P>0.05) , respectively. CuZn-SOD in GroupⅠa ndⅠincreased by 1.07%, 9.47% (P>0.05), respectively, while that in the group ofⅠdecreased by 0.9% (P>0.05). Levels of ALT in GroupⅠandⅠincreased by 26.04%, 41.01% (P<0.05), respectively, but the groupⅠincreased by 13.87% (P>0.05). AST level in GroupⅠ,ⅠandⅠincreased by 11.43%, 15.55%, 22.43% (P>0.05), respectively.Compared with the control group, INS levels in GroupⅠandⅠdecreased by 11.11%, 4.97% (P>0.05), respectively, and IGF-Ⅰin GroupⅠ,ⅠandⅠhad decreased by 2.19%, 6.17% and 19.09 % (P>0.05), respectively. T3 in GroupⅠandⅠdecreased by 8.02% and 12.96% (P>0.05), respectively and T4 of GroupⅠ,ⅠandⅠdecreased by 9.53% , 5.48% and 9.11% (P>0.05), respectively.Compared with the control group, Cu content in the groupⅠ,ⅠandⅠincreased by 10.43% (P>0.05), 22.64%, 19.53% (P<0.05). The Zn levels in serum of GroupsⅠa ndⅠdecreased by 10.64 %, 2.67% (P>0.05) , respectively. However, that of GroupⅠincreased by 25.75% (P<0.05). The Fe levels in serum of GroupⅠandⅠincreased by 34.8%, 40.31% (P<0.05), respectively.Compared with the control group, the Cu content in fece of GroupⅠincreased by 19.89% (P<0.05), but those in GroupⅠandⅠdecreased by 36.36%, 60.23% (P<0.05) , respectively. The Fe content in fece of GroupⅠhad increased by 54.6% (P<0.05). There was no significant difference between GroupsⅠandⅠ(P>0.05). The Zn content in fece had no remarkable diffrence among the groups (P>0.05)。In conclusion, copper glycine had no significant effect on promoting growth of weanling piglets in our experiment groups, but it can improve their immunility. The diet for weanling piglet mixed 62.5 mg·kg-1 copper glycine can significently decreasd the FG and facal copper content. Thus, 62.5 mg·kg-1 copper glycine is the optimal level for weanling piglets.