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The Influence Of PCI On Heart Rate Variability Of Coronary Heart Disease Patient

Posted on:2005-12-20Degree:MasterType:Thesis
Country:ChinaCandidate:S G JiangFull Text:PDF
GTID:2144360125469763Subject:Internal Medicine
Abstract/Summary:PDF Full Text Request
Heart rate variability (HRV) , referring to the phenomenon that heart rate range regularly within a certain period, is the indices of sympathetic and para-sympathetic activity. It has been tested by clinical studies that reduced HRV is an independent prognostic determinant in the patients with myocardial infarction ( MI) and sudden cardiac death. Although PTCA helps improve the condition of the patients, its influence on HRV is still a debatable question. Doing research on PCI patients compared with the control group who do not undergo PCI, we aim to evaluate the influence of PCI on heart rate variability of coronary heart disease ( CHD) patient.Materials1. PCI group: 38 patients are involved in the research: 15 with AMI, and 23 with unstable angina pecloris. All of them are chosen from the No. 463 Hospital of Liberation Army. Among the patients to be tested 29 are males, and 9 are females. Their average age is (62. 1 + 18. 1) years old (from 35 to 74). They stayed in hospital for (16.7+3.0) days on average.2. Control group: They are CHD patients without PCI treatment. 35 patients are involved in the research; 13 with AMI, and 22 with unstable angina pectoris. Among the patients in this group 27 are males, and 8 are females. Their average age is 58. 6 +14. 1) years old (from 40 to 72). They stayed in hospital for (17.0+2.8) days on average.There is no outstanding distinction between the two groups in gender and age.MethodsP1. Record of cardiogram: As to the PCI group, the 24 - hour record of their cardiogram were made before the operation and one week, two weeks and 3 months respectively after it. As to the control group, the 24 - hour record of their cardiogram were made before the regular medicine treatment and one week, two weeks and 3 months respectively after it. The method to analyze and deal with materials from both groups is the same.2. PCI; With the help of the X - DAOJING made in Japan and the supplied computer system of QCA, all the patients in the PCI group were required to take coronary angiography, in which way to decide whether to undergo the PCI or not.3. Analysis of HRV: The figures of patients' HRV were calculated by the automatic analytical system of the computer, through person - to - computer communication. The unit of time domain index is " ms" , including: SDNN, SDANN, SDNN Index. As for frequency domain index, it includes: TP and HF.4. Statistical treatment: The tested figures are expressed by way of the formula : average + standard deviation ( x + s). T - testing was used to analyze and treat the figures through the Excel software. If P is less than 0. 05 ( P < 0. 05), it is valid statistically.Results1. Comparison of HRV within the PCI group:The condition of HRV recorded one week, two weeks and 3 months after the operation was compared with that recorded before the operation. Result: The HRV recorded one week after the operation did not vary distinctively against that before the operation. The HRV recorded after two weeks did vary distinctively a-gainst that before the operation. (P < 0.05). The HRV recorded three months after varied so much against that before the operation that it arrived at the criterion (P < 0.01).2. Comparison of HRV within the control group:As for this group, the HRV was obtained through the 24 - hour record of their cardiogram after they took the regular medicine treatment. Compared with the HRV recorded before, the result is as follows: The HRV recorded one week, two weeks and 3 months respectively after the treatment strengthened e-nough to reach the.standard (P < 0.05) set before.3. Comparison of HRV between the PCI group and the control group: The result is as follows: The HRV of the control group recorded one week after the operation did vary distinctively against that of the PCI group (P < 0. 05). The HRV of the PCI group recorded two weeks after varied to some degree against that of the control group, but did not reach the standard set before ( P < 0. 05). The HRV of the PCI group recorded...
Keywords/Search Tags:percutaneous coronary intervention ( PCI), coronary heart disease (CHD), heart rate variability ( HRV)
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