Study On Transrectal Ultrasonography Of The Prostate And Transrectal Ultrasound Guided Prostate Biopsy

Objective: To evaluate the clinical application of transrectal colourDoppler ultrasonography and transrectal ultrasound guided prostatebiopsy. Methods: Part 1: A total of 46 patients referred to abnormal digitalrectal examination (DRE) and/or elevated serum prostate-specificantigen (PSA) were examined by transabdominal ultrasonography andtransrectal colour Doppler ultrasonography. Prostate size, prostatevolume, PSA, prostate-specific antigen density (PSAD), colour bloodflow signals and peak systolic velocity (PSV), end diastolic velocity(EDV), resistant index (RI) of the lesions were measured and analyzed.Part 2: A total of 46 patients referred to abnormal DRE and/or elevatedserum PSA were underwent transrectal ultrasound guided sextantbiopsies of the prostate. Results: Part 1: Transrectal colour Doppler ultrasonography in thediagnosis of prostate cancer (PCA) had a sensitivity of 75.0% and aspecificity of 58.8%. The transrectal ultrasonic imaging was clear. Therate of transrectal ultrasonography for prostate stone, cyst, lesiondetection was higher than that of transabdominal ultrasonography(P<0.01). The prostate width of the prostate cancer group was longerthan that of the benign prostate hyperplasia (BPH) group (P<0.05). Thevalues of PSA and PSAD in the PCA group were higher than those in theBPH group (P<0.01). Compared with the BPH group, in the PCA groupthe prostate revealed the blood flow more abundant (P<0.05), the lesionsrevealed the shapes more irregular and the rims unclear and the PSV,EDV of the lesions were higher than those in the BPH group (P<0.01).Part 2: The positive rate of prostate biopsy was 26.1%. The pathologicstudy proved 30 BPH, 12 PCA, 3 prostatic intraepithelial neoplasia(PIN), 1 atypical adenomatous hyperplasia (AAH). No severecomplications were occurred among the patients who underwenttransrectal ultrasound guided sextant biopsies of the prostate. Conclusions: Transrectal colour Doppler ultrasonography is helpfulto the diagnosis and differentiating diagnosis of the prostate disease. Itwas safe, slightly painful, shortly and without anaesthesia during thetransrectal ultrasound guided sextant biopsies of the prostate. It is helpfulto the differentiation of the prostate disease and is beneficial to diagnosePCA of early stage.