Clinical Characteristics And Analysis Of Prognostic Factors In Postoperative Recurrent Laryngeal Cancer

Objective: To analyze the clinical features and prognostic factors of recurrent postoperative laryngeal carcinoma。Methods: 51 patients who was diagnosed and operated in The First Hospital of JiLin University and sufferred postoperative recurrent laryngeal carcinoma were retrospectively investigated. Survival analysis was performed by Kaplan-Meier method;comparison among groups was performed using log-rank test.Results:The 5-year survive rate for patients with recurrent postoperative laryngeal carcinoma were 45.1%, the median survive time were 39.58 months;The patients with higher TNM classification had a greater risk of recurrence; The recurrent rate of stage 1,2,3,4 was 6.10%, 8.49%, 10.06%, 14.61% by separate; The duration between operation and recurrence were mostly in 1 year(38/51),and the faverate recurrent sites were neck lymph node(27/51) and locoregional recurrence (16/51);Univariate analysis revealed that the factors impacting the prognosis were the TNM classification, the original occur site,the histological grade, postoperate therapy,the reoccur site and the reoccur tumor size(P〈0.05). Conclusion:The patients with higher TNM classification had a greater risk of recurrence; The duration between operation and recurrence were mostly in 1 year;Most tumor reoccur in neck lymph node and secondly locoregional recurrence; The TNM classification, the original occur site,the histological grade, postoperate therapy,the reoccur site and the reoccur tumor size were the factors which effect the prognosis.