Experimental Study On The Effect Of Acupuncture To The Peripheryfacial Paralysiss Rabbit Facial Nerve Nucleus NGF Expression

Goal : Through the acupuncture to the periphery facial paralysis rabbit facial nerve nucleus NGF expression experimental study, promulgates the acupuncture promotion facial nerve damage regeneration repair the mechanism, discovered the new acupuncture function target spot, the facial paralysis clinical curative effect provides the scientific experiment for the acupuncture treatment periphery to rest on.Method: 1.Japanese big ear white rabbit 120, female and male are half and half.2.Stochastically divides into 5 groups 120 rabbits (each group of 24) False surgery group: Left side the incision the face skin, after exposes the facial nerve to suture. Model group: After makes the mold not to give any handling. Western medicine group: After makes the mold to give Vitamin B₁, the Vitamin B₁₂ + dexamethasone intramuscular injection.Hand needle group: After makes the mold to give the acupuncture treatment.Electricity needle group: After makes the mold to give the electricity needle treatment. After each group divides into the technique 7d, 14d, 21d, when the 28d four treatments compartment.3.Target determination: â‘  Determines the NGF protein masculine gender expression through the immunity histochemistry. (2) survey treatment various time rabbit facial nerve MNCV.4.3Statistical method: Makes statistics analysis processing using the SPSS 14.0 software, in the group, the group with the variance analysis, the q examination, the t examination, P<0.05 has in statistics the significance.RESULT: Rabbit facial MNCV: â‘  The western medicine group, the hand needle group, the electricity needle group curative effect surpasses the model group (*P<0.05 , **P<0.01);Hasstatistics significance. (2) The electricity needle group curative effect surpasses the hand needle group, the western medicine group (qP<0.05);Has statistics significance.NGF of rabbit FNN: CD The western medicine group, the hand needle group, the electricity needle group higher the model group on the positive ratio of NGF (*P<0.05, **p<0.01);Has statistics significance. (2) The electricity needle group higher the western medicine groupand the hand needle group. (AP<0.05) , Has statistics significance. Conclusion: 1.Acupuncture can promote significantly the regeneration and renovation of injuried PN of the rabbit facial never, and the therapeutic effect of electrical needle is better than that of the hand-needle.2.Acupuncture can abate the hydrops of the injuried facial nerve of rabbit, protect PN and prevent retrograde degeneration. 3.Acupuncturecan improve the recovery ratio of injuried facial nerve of rabbit. 4.Acupuncture can improve facility appearance of injuried schwann cell,impel it to secrete NGF and prolong the effective period.