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Observation Of Nerve Root Structure And Function After Coblation Of Rabbit Nucleus Pulposus

Posted on:2007-10-14Degree:MasterType:Thesis
Country:ChinaCandidate:Y JiangFull Text:PDF
GTID:2144360185471252Subject:Surgery
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Background and ObjectiveLumbar disc herniation (LDH) is a common cause of backleg pain. Up to now open operation treatment has 70 years of history. Because traditional open operations bring more injures and complications, so more and more minimal invasive surgical techniques, such as chemonucleolysis, percutaneous laser disc decompression, micro endoscopic discectomy, were introduced to clinical practice and show good results. Coblation is a new technology developed to treat disc herniation in recent years. Since 2000 this technique was successfully applied for LDH by coblation of nucleus pulposus in American, scholars reported a lot of clinical series. But most clinical practices were limited to percutaneous nucleoplasty, which ablate nucleus pulposus by insertion of the coblation-channeling wand. A former study suggested that kept wand 2mm away from never tissues can avoid never injury when ablation, other report suggested less than 11mm could cause never damage. Anatomy of vertebral canal is complex, it has a little volume and abundant neurovascular tissues. No existing methods can remove nucleus pulposus effectively, stop bleeding and shape annular fibrosus at same time. Although coblation has these advantages, there were few reports indicated if coblation can be safely performed from posterior approach through vertebral canal.In this experiment, we perform coblation to rabbit from posterior approach and through spine canal, observe structure and conduction velocity of nerve roots, then analyze if coblation can influence nerve root structure and conduction function. By doing this we can judge safety of coblaion and provide experimental evidences for...
Keywords/Search Tags:Lumbar vertebrae, Intervertebral disk displacement, Coblation, Histomorphology, Nerve conduction velocity
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