Effect Of Pulsed Electromagnetic Fields Of Different Magnetic Intensity On Bone Mineral Density, Bone Calcium Content And Biomechanical Properties Of Femur In Ovariectomized Rats

Objective: The purpose of this study was to observe the effect of PEMFs of different intensity on bone mineral density, bone calcium content and biomechanical properties of femur in ovariectomized rats, so as to find out the intensity for the best therapeutic efficacy.Materials and Methods: Fifty female SD rats were randomly divided into five groups: (1) sham-operated control (no PEMFs treatment), (2) ovariectomized control (no PEMFs treatment), (3) ovariectomized I (PEMFs treatment at 8HZ frequency with 0.77mT intensity, 40min daily for 30 days), (4) ovariectomized II (PEMFs treatment at 8HZ frequency with 3.82mT intensity, 40min daily 30 days), and (5) ovariectomizedIII(PEMFs treatment at 8HZ frequency with 9.87mT intensity, 40min daily 30 days). Except for 10 rats of the sham-operated control group, a standardized ovariectomy was used in every rat. Estradiol (E₂) of serum, bone mineral density (BMD), boen calcium contents and biomechanical properties (peak load, maximum displacement, maximum energy absorption, maximum stress, maximum strain and modulus of elasticity) of femur were assessed at 30 days after PEMFs treatment. Result: â‘  The E₂ values of the sham-operated control group were...