Effect Of Pulsed Electromagnetic Fields Of Different Frequencies On Bone Mineral Density, Bone Calcium Content And Biomechanical Properties Of Femur In Ovariectomized Rats

Background: Experimental and clinical data indicate that pulsed electromagnetic fields (PEMFs) can relieve osteoporotic pain and improve bone mass without side-effects of the traditional treatment. PEMFs have been partly used in the rehabilitation of osteoporosis. However, the frequency for the best therapeutic efficacy is unclear.Objective: The purpose of this study was to observe the effect of PEMFs of different frequencies on bone mineral density, bone calcium content and biomechanical properties of femur in ovariectomized rats, so as to find out the frequency for the best therapeutic efficacy.Materials and Methods: Fifty female SD rats were randomly divided into five groups: (1) SHAM control (no PEMFs treatment), (2) OVX control (no PEMFs treatment), (3) OVX I (PEMFs treatment at 2HZ frequency with 3.8mT intensity, 40min daily for 30 days), (4) OVXII (PEMFs treatment at 8HZ frequency with 3.8mT intensity, 40min daily for 30 days), and (5) OVX III(PEMFs treatment at 16HZ frequency with 3.8mT intensity, 40min daily...