Studies On Lyophilization Injection Of Radix Isatidis

Radix Isatidis is a traditional Chinese medicine which is used with a long history in China, it is famous used for heat-clearing and detoxifcation , first recorded in a herbal book-Shennong Bencao Jing, then in every edition of Bencao and Chinese Pharmacopoeias. Radix Isatidis used at clinic at present include two kinds: the the dried radix of Isatis indigotica Fort, of Crucifer and the dried radix of Strobilanthes cusia (Nees) O. Ktze. Of Acanthaceae. Chinese pharmacopoeia (2005) regulates Radix Isatidis as the dried radix of Isatis indigotica Fort. of the Crucifer and Isatis indigotica Fort, is the main source of Radix Isatidis.Radix Isatidis is often used to treat viral disease and bacterial infection disease. Through studies on the pharmacodynatics of Radix Isatidis, scientists find that Radix Isatidis have the functions of antibacterial , antivirus, resisting bacterial endotoxin, strengthening immunity , anticancer and blood circulation promoting. Especially it has a positive effective function in the treatment of the antivirus. Numerous literatures report that Radix Isatidis has a good function of treating or preventing to the influenza caused by virus, hepatitis B , simple bleb , viral myocarditis , nephropathy syndrome , bleed hot , parotitis and many other kinds of disease. Radix Isatidis is one of a few traditional Chinese medicines generally acknowledged with good antiviral function.In the clinical practice, we find the injection of Radix Isatidis and the decoction of Radix Isatidis have positive antiviral curative function . Because the preparing technique of the original injection is crude, it contains plenty of impurity which frequently causes the immediate hypersensitivity at clinic in a large amount and was being restricted in the clinical practice. According to the documents and literatures of the experiment and the clinic , the total amino acid and the nucleoside are confirmed as the primary active ingredients which has the antiviral function.The purpose of this paper is to increase the percentage of the active ingredients in preparation on the basis of the craft of preparing the injection of Radix Isatidis , reduce the content of the impurity , improve the the antiviral curative function and reduce its immediate...