Clinical Studies On Children's Bronchial Asthma In Catabasis Treated With Fangxiao Granule

Objective:By observing and probing into the etiology,pathogenesis,prevention and cure medicine of children's bronchial asthma in catabasis in theories and clinic,we try to find a kind of safe,effective,congvenient,economical medicine of children's bronchial asthma in catabasis and probe into the prevention and cure elements on air-way inflammation in catabasis. Methods:In clinical study,90 bronchial asthma children in catabasis are randomly divided into 3 groups,treated with Fangxiao Granule, Gu Ben Ke Chuan Tablet and Budesonide Powder for Inhalation for three month.We observe the change of the children's cardinal symptom,objective sign,frequency,pulmonary function, pulmonary microcirculation and laboratory examination.After that,we compare the treatment group with the control groups. Result:The clinical study shows that the treatment group is better than the control groups in children's cardinal symptom, objective sign, frequency, pulmonary function, pulmonary microcirculation and laboratory examination.The Fangxiao Granule can improve the immune function and reduce the content of inflammatory factor IL-4 and immunological factor IgE in the serum of bronchial asthma children in catabasis, and EOS count in the peripheral blood, alleviate air-way tracheospasm and have significant differences compared with Gu Ben Ke Chuan Tablet and Budesonide Powder for Inhalation groups (P<0.01). Conclusion: Fangxiao Granule have good prevention and cure function on asthma children's air-way inflammation in catabasis.