The Clinical Effect On The Integrating Treatment Of Lupus Nephritis In Mildly Active With Traditional Chinese And Western Medicine

[Purpose] : To observe the clinical effect of the treatment combining traditional Chinese and western medicine on lupus nephritis (LN) in Mildly active and analyze the rate of relapsing , the incidence of adverse reactions.[Method] : 40 cases of patients with lupus nephritis in Mildly active, randomly divided into treatment and control groups by 1:1 ratio. Treat the conventional treatment group with Chinese medicine Syndrome addition and subtraction on the basis of hormone therapy, and with conventional western medicine treatment for the control group. Observe the treatment of symptoms and signs, blood, complement C3, C4, 24h urine protein, liver and kidney function indicators of patients and analyze the patients' clinical efficacy and recurrence, the occurrence of adverse reactions in each group during one year.[Results] : (1) There is significant difference between the total efficiency of treatment group (95.0%) and the control group (70.0%) (P <0. 05) ; (2) it has statistical significance of the difference between the relapsing rate of the treatment group and the control group (P <0. 05); (3) it has statistical significance of the difference between the adverse reaction rates of the treatment group and the control group (P <0.05); (4) the treatment group' 24hs urine protein is significant lower than the control group' after treatment (P <0. 01) ; (5) the treatment group' complement C3,C4 is significant richer than the control group' after treatment (P<0.01) . (6) compared with the control group the treatment group can be effective in reducing the use of hormones, and the difference between them is very significant(P<0. 01).[Conclusion] : The treatment group' s effect is better than the control group' s on improving the clinical symptoms, controlling LN recurrence, reducing the incidence of adverse reactions to reduce the use of hormones, lowering urinary protein.