The Effects Of Bone Mineralization To The Patients With Senile Osteoporosis Treated With Stasis-Eliminating Vein Dredging Therapy

Objective:From the clinical angulation, to observe the effects of bone mineralization to the patients with Senile Osteoposis treated with Stasis-Eliminating Vein Dredging therapy, and to approach the pathogeny of Senile Osteoposis and the mechanism of the treatment to SOP with Stasis-Eliminating Vein Dredging therapy,to supply scientific theory basis for clinical application..Methods:60 Patients with Blood-Stasis type Senile Osteoporosis, were divided into two groups randomly, 30 patients per group: the treat group (treated with the Huoxuetongmai capsule and Caltrate D 600 chew tablet);the control group(treated with Caltrate D 600 chew tablet).Appraised the clinical stituation integrative scores ,Nail fold Microcirculation scores and Hemorheology, and determined anterior-posterior position lumbar2～4 vertebra body BMD, BGP, BALP, before and after treated 1 year, then contrast intragroup and selfgroup. Depending on the standard of curative effect, contrast the difference of curative effect between two groups.Results:1. Two groups clinical appearance integrative scores and Nail fold Microcirculation scores were lower than pretreatment after 1 year, with significant difference(P < 0.01), the change of the control group is also lower, but no significant significance(P > 0.05). There is a significant difference between the two groups (P<0.01). To illustrate that Stasis-Eliminating Vein Dredging principle to the patients with Blood-Stasis type SOP can amend the clinical symptoms of Blood-Stasis and the microcirculation disturbance.2. The hemorheology level of the treat group was lower than the pretreatment after 1 year, with significant difference(P < 0.01). the change of the control group has no significant difference (P > 0.05). There is a significant difference between the two groups (P < 0.01). To illustrate that Stasis-Eliminating Vein Dredging principle to the patients with Blood-Stasis type SOP can amend the hemorheology.3. The post-treatment Lumbar vertebra BMD were increased both in the treat group and the control group, with significant difference in the treat group (P < 0.01), but there is not significant difference in the control group (P > 0.05).There is a significant difference between the two groups (P < 0.01). To illustrate that Stasis-Eliminating Vein Dredging principle to the patients with Blood-Stasis type SOP can improve the bone mineral contents(BMC) and BMD.4. The BGP level in the blood of the treat group were improved than pretreatment and the BALP level in the blood of the treat group were lowered than pretreatment after 1 year, with significant difference(P < 0.01), the change of the control group has no significant significance(P > 0.05). There is a significant difference between the two groups (P < 0.01). To illustrate that Stasis-Eliminating Vein Dredging principle to the patients with Blood-Stasis type SOP can improve the level of bone metabolism,promote bone formation.5. The total availability rate is 93.33% in the treat group, and is 73.33% in the control group, which has a significant difference between the two groups (P < 0.05). To illustrate that Stasis-Eliminating Vein Dredging principle to the patients with Blood-Stasis type SOP can amend the lumbodynia that is main clinical situation,improve the quality of life.Conclusions:1. The patients of Senile Osteoposis not only exist evident Blood-Stasis clinical situation, but also exist objective pathological change of Blood-Stasis.Its morbidity is intimate correlate to the Blood-Stasis and the Blood-Stasis is one of the important pathogenetic factors.2. Stasis-Eliminating Vein Dredging principle to the patients with Blood-Stasis type SOP, can amend the clinical symptoms of Blood-Stasis and the microcirculation disturbance,thereby amend the lumbodynia that is main clinical situation,improve the quality of life.3. Stasis-Eliminating Vein Dredging principle to the patients with Blood-Stasis type SOP can improve the level of bone metabolism,promote the bone mineralization,improve the bone mineral contents(BMC) and BMD,thereby improve the curative effect of bone mineralization drugs.